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CNIH1 cornichon family AMPA receptor auxiliary protein 1 [ Homo sapiens (human) ]

Gene ID: 10175, updated on 13-May-2022

Summary

Official Symbol
CNIH1provided by HGNC
Official Full Name
cornichon family AMPA receptor auxiliary protein 1provided by HGNC
Primary source
HGNC:HGNC:19431
See related
Ensembl:ENSG00000100528 MIM:611287; AllianceGenome:HGNC:19431
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CNIH; CNIL; CNIH-1; TGAM77
Summary
Predicted to be involved in immune response and signal transduction. Predicted to be located in ER to Golgi transport vesicle membrane; endoplasmic reticulum membrane; and endoplasmic reticulum-Golgi intermediate compartment membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver (RPKM 47.9), duodenum (RPKM 41.3) and 25 other tissues See more
Orthologs
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Genomic context

See CNIH1 in Genome Data Viewer
Location:
14q22.2
Exon count:
5
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (54423561..54441374, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (48628725..48646539, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (54890279..54908092, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene VISTA enhancer hs1414 Neighboring gene cyclin dependent kinase inhibitor 3 Neighboring gene glia maturation factor beta Neighboring gene cell growth regulator with ring finger domain 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC117156

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in immune response TAS
Traceable Author Statement
more info
PubMed 
involved_in signal transduction TAS
Traceable Author Statement
more info
PubMed 
involved_in vesicle-mediated transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in ER to Golgi transport vesicle membrane TAS
Traceable Author Statement
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane TAS
Traceable Author Statement
more info
 
located_in endoplasmic reticulum-Golgi intermediate compartment membrane TAS
Traceable Author Statement
more info
 
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
protein cornichon homolog 1
Names
T-cell growth-associated molecule 77
cornichon homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_005776.3NP_005767.1  protein cornichon homolog 1

    See identical proteins and their annotated locations for NP_005767.1

    Status: VALIDATED

    Source sequence(s)
    AF104398, AL359792, AY358635
    Consensus CDS
    CCDS9717.1
    UniProtKB/Swiss-Prot
    O95406
    UniProtKB/TrEMBL
    B2R4P1
    Related
    ENSP00000216416.4, ENST00000216416.9
    Conserved Domains (1) summary
    pfam03311
    Location:7135
    Cornichon; Cornichon protein

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

    Range
    54423561..54441374 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060938.1 Alternate T2T-CHM13v2.0

    Range
    48628725..48646539 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001009551.1: Suppressed sequence

    Description
    NM_001009551.1: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.