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SPECC1L-ADORA2A SPECC1L-ADORA2A readthrough (NMD candidate) [ Homo sapiens (human) ]

Gene ID: 101730217, updated on 13-May-2022

Summary

Official Symbol
SPECC1L-ADORA2Aprovided by HGNC
Official Full Name
SPECC1L-ADORA2A readthrough (NMD candidate)provided by HGNC
Primary source
HGNC:HGNC:49185
See related
Ensembl:ENSG00000258555 AllianceGenome:HGNC:49185
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This locus represents naturally occurring readthrough transcription between the neighboring SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) genes on chromosome 22. The readthrough transcript is a candidate for nonsense-mediated mRNA decay (NMD) and is unlikely to produce a protein product. [provided by RefSeq, Jun 2013]
Expression
Ubiquitous expression in testis (RPKM 16.3), thyroid (RPKM 10.6) and 25 other tissues See more
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Genomic context

See SPECC1L-ADORA2A in Genome Data Viewer
Location:
22q11.23
Exon count:
20
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (24270817..24442360)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (24732427..24903994)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (24666785..24838328)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene POM121 transmembrane nucleoporin like 9, pseudogene Neighboring gene ribosomal protein S10 pseudogene 29 Neighboring gene BCR pseudogene 1 Neighboring gene sperm antigen with calponin homology and coiled-coil domains 1 like Neighboring gene uncharacterized LOC105372960 Neighboring gene ADORA2A antisense RNA 1 Neighboring gene adenosine A2a receptor Neighboring gene beta-ureidopropionase 1 Neighboring gene guanylyl cyclase domain containing 1 Neighboring gene small nuclear ribonucleoprotein D3 polypeptide

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_103546.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AB209022, AP000354, AP000355
    Related
    ENST00000358654.2

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    24270817..24442360
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    24732427..24903994
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)