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Bco1 beta-carotene oxygenase 1 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101724039, updated on 1-Mar-2025
Gene symbol
Bco1
Gene description
beta-carotene oxygenase 1
Locus tag
GW7_17545
See related
Ensembl:ENSHGLG00000017639 RGD:18933373
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Also known as
Bcmo1
Orthologs
human mouse all
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See Bco1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624746.1 (6146338..6181020, complement)

NW_004624746.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101723428 Neighboring gene gigaxonin Neighboring gene uncharacterized LOC110348753 Neighboring gene polycystin-1-like protein 2 Neighboring gene glycine cleavage system protein H

Genomic Sequence:
NW_004624746 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables beta-carotene 15,15'-dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables carotenoid dioxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in carotene catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in retinal metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
beta,beta-carotene 15,15'-dioxygenase
Names
Beta,beta-carotene 15,15'-monooxygenase
beta-carotene 15,15'-monooxygenase 1

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624746.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    6146338..6181020 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004842798.3 → XP_004842855.1  beta,beta-carotene 15,15'-dioxygenase isoform X3

    UniProtKB/TrEMBL
    A0AAX6P3P7, G5B1X2
    Related
    ENSHGLP00000024736.1, ENSHGLT00000024958.1
    Conserved Domains (1) summary
    pfam03055
    Location:10 → 519
    RPE65; Retinal pigment epithelial membrane protein

  2. XM_021256672.1 → XP_021112331.1  beta,beta-carotene 15,15'-dioxygenase isoform X4

    UniProtKB/TrEMBL
    A0AAX6SSG1, G5B1X2
    Conserved Domains (1) summary
    pfam03055
    Location:1 → 479
    RPE65; Retinal pigment epithelial membrane protein

  3. XM_021256673.1 → XP_021112332.1  beta,beta-carotene 15,15'-dioxygenase isoform X5

    UniProtKB/TrEMBL
    A0AAX6SRI1, G5B1X2
    Conserved Domains (1) summary
    pfam03055
    Location:63 → 472
    RPE65; Retinal pigment epithelial membrane protein

  4. XM_021256674.1 → XP_021112333.1  beta,beta-carotene 15,15'-dioxygenase isoform X6

    UniProtKB/TrEMBL
    A0AAX6SX64
    Conserved Domains (1) summary
    pfam03055
    Location:63 → 434
    RPE65; Retinal pigment epithelial membrane protein

  5. XM_021256671.1 → XP_021112330.1  beta,beta-carotene 15,15'-dioxygenase isoform X2

    UniProtKB/TrEMBL
    A0AAX6SX42, G5B1X2
    Conserved Domains (1) summary
    pfam03055
    Location:63 → 558
    RPE65; Retinal pigment epithelial membrane protein

  6. XM_021256670.1 → XP_021112329.1  beta,beta-carotene 15,15'-dioxygenase isoform X1

    UniProtKB/TrEMBL
    A0AAX6STZ9, G5B1X2
    Conserved Domains (1) summary
    pfam03055
    Location:63 → 558
    RPE65; Retinal pigment epithelial membrane protein
Nucleotide Protein
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