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LOC101722738 5-hydroxyisourate hydrolase [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101722738, updated on 1-Mar-2025
Gene symbol
LOC101722738
Gene description
5-hydroxyisourate hydrolase
Locus tag
GW7_12411
See related
Ensembl:ENSHGLG00000017690 RGD:18933375
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
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See LOC101722738 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
4
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624746.1 (26873..29564)

NW_004624746.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110348728 Neighboring gene growth arrest specific 8 Neighboring gene dysbindin domain containing 1 Neighboring gene AFG3-like protein 1

Genomic Sequence:
NW_004624746 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxyisourate hydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in purine nucleobase metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
5-hydroxyisourate hydrolase

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624746.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    26873..29564
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004842602.2 → XP_004842659.1  5-hydroxyisourate hydrolase isoform X2

    See identical proteins and their annotated locations for XP_004842659.1

    UniProtKB/TrEMBL
    G5APG7
    Related
    ENSHGLP00000024811.1, ENSHGLT00000025033.1
    Conserved Domains (1) summary
    cd05822
    Location:6 → 118
    TLP_HIUase; HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). ...

  2. XM_004842600.1 → XP_004842657.1  5-hydroxyisourate hydrolase isoform X1

    UniProtKB/TrEMBL
    A0AAX6P3E3
    Conserved Domains (1) summary
    cd05822
    Location:71 → 183
    TLP_HIUase; HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). ...
Nucleotide Protein
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