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Gabra2 gamma-aminobutyric acid type A receptor alpha2 subunit [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101720776, updated on 20-Jun-2018

Summary

Gene symbol
Gabra2
Gene description
gamma-aminobutyric acid type A receptor alpha2 subunit
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs

Genomic context

See Gabra2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624761.1 (20688819..20819487)

NW_004624761.1Genomic Context describing neighboring genes Neighboring gene ras-related protein Rab-5A pseudogene Neighboring gene sec1 family domain-containing protein 1 pseudogene Neighboring gene 60S ribosomal protein L37 pseudogene Neighboring gene gamma-aminobutyric acid type A receptor gamma1 subunit

Genomic regions, transcripts, and products

Genomic Sequence:
NW_004624761 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Pathways from BioSystems

  • GABAergic synapse, organism-specific biosystem (from KEGG)
    GABAergic synapse, organism-specific biosystemGamma aminobutyric acid (GABA) is the most abundant inhibitory neurotransmitter in the mammalian central nervous system (CNS). When released in the synaptic cleft, GABA binds to three major classes o...
  • GABAergic synapse, conserved biosystem (from KEGG)
    GABAergic synapse, conserved biosystemGamma aminobutyric acid (GABA) is the most abundant inhibitory neurotransmitter in the mammalian central nervous system (CNS). When released in the synaptic cleft, GABA binds to three major classes o...
  • Morphine addiction, organism-specific biosystem (from KEGG)
    Morphine addiction, organism-specific biosystemMorphine is an alkaloid from the plant extracts of opium poppy. Although morphine is highly effective for the treatment of pain, it is also known to be intensely addictive. We now know that the most ...
  • Morphine addiction, conserved biosystem (from KEGG)
    Morphine addiction, conserved biosystemMorphine is an alkaloid from the plant extracts of opium poppy. Although morphine is highly effective for the treatment of pain, it is also known to be intensely addictive. We now know that the most ...
  • Neuroactive ligand-receptor interaction, organism-specific biosystem (from KEGG)
    Neuroactive ligand-receptor interaction, organism-specific biosystem
    Neuroactive ligand-receptor interaction
  • Neuroactive ligand-receptor interaction, conserved biosystem (from KEGG)
    Neuroactive ligand-receptor interaction, conserved biosystem
    Neuroactive ligand-receptor interaction
  • Nicotine addiction, organism-specific biosystem (from KEGG)
    Nicotine addiction, organism-specific biosystemNicotine is one of the main psychoactive ingredients in tobacco that contributes to the harmful tobacco smoking habit. A common feature of addictive drugs, including nicotine, is that they increase d...
  • Nicotine addiction, conserved biosystem (from KEGG)
    Nicotine addiction, conserved biosystemNicotine is one of the main psychoactive ingredients in tobacco that contributes to the harmful tobacco smoking habit. A common feature of addictive drugs, including nicotine, is that they increase d...
  • Retrograde endocannabinoid signaling, organism-specific biosystem (from KEGG)
    Retrograde endocannabinoid signaling, organism-specific biosystemEndogenous cannabinoids (endocannabinoids) serve as retrograde messengers at synapses in various regions of the brain. The family of endocannabinoids includes at least five derivatives of arachidonic...
  • Retrograde endocannabinoid signaling, conserved biosystem (from KEGG)
    Retrograde endocannabinoid signaling, conserved biosystemEndogenous cannabinoids (endocannabinoids) serve as retrograde messengers at synapses in various regions of the brain. The family of endocannabinoids includes at least five derivatives of arachidonic...
  • Taste transduction, organism-specific biosystem (from KEGG)
    Taste transduction, organism-specific biosystemFive basic tastes are recognized by humans and most other animals - bitter, sweet, sour, salty and umami. In vertebrates, taste stimuli are detected by taste receptor cells (TRCs). At least three dis...
  • Taste transduction, conserved biosystem (from KEGG)
    Taste transduction, conserved biosystemFive basic tastes are recognized by humans and most other animals - bitter, sweet, sour, salty and umami. In vertebrates, taste stimuli are detected by taste receptor cells (TRCs). At least three dis...

General protein information

Preferred Names
gamma-aminobutyric acid receptor subunit alpha-2

NCBI Reference Sequences (RefSeq)

RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624761.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    20688819..20819487
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013073996.2XP_012929450.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X2

    Conserved Domains (3) summary
    TIGR00860
    Location:25500
    LIC; Cation transporter family protein
    pfam02931
    Location:43250
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:257497
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
  2. XM_004849776.3XP_004849833.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X1

    See identical proteins and their annotated locations for XP_004849833.1

    UniProtKB/TrEMBL
    A0A0P6JDV9
    Conserved Domains (1) summary
    cl27321
    Location:25440
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
  3. XM_004849775.3XP_004849832.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X1

    See identical proteins and their annotated locations for XP_004849832.1

    UniProtKB/TrEMBL
    A0A0P6JDV9
    Conserved Domains (1) summary
    cl27321
    Location:25440
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
  4. XM_004849777.3XP_004849834.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X1

    See identical proteins and their annotated locations for XP_004849834.1

    UniProtKB/TrEMBL
    A0A0P6JDV9
    Conserved Domains (1) summary
    cl27321
    Location:25440
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
  5. XM_021262394.1XP_021118053.1  gamma-aminobutyric acid receptor subunit alpha-2 isoform X1

    Conserved Domains (1) summary
    cl27321
    Location:25440
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
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