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Plekhh1 pleckstrin homology, MyTH4 and FERM domain containing H1 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101717797, updated on 1-Mar-2025

Summary

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Gene symbol
Plekhh1
Gene description
pleckstrin homology, MyTH4 and FERM domain containing H1
Locus tag
GW7_03710
See related
Ensembl:ENSHGLG00000006646 RGD:18904698
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Plekhh1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
30
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624734.1 (33411271..33456003, complement)

NW_004624734.1Genomic Context describing neighboring genes Neighboring gene cytochrome c oxidase subunit 5B, mitochondrial pseudogene Neighboring gene retinol dehydrogenase 11 Neighboring gene vesicle transport through interaction with t-SNAREs 1B Neighboring gene arginase 2 Neighboring gene phosphatidylinositol glycan anchor biosynthesis class H Neighboring gene transmembrane protein 229B Neighboring gene proliferation-associated protein 2G4

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624734 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pleckstrin homology domain-containing family H member 1
Names
Pleckstrin-like protein domain-containing family H member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624734.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    33411271..33456003 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013067579.2 → XP_012923033.1  pleckstrin homology domain-containing family H member 1 isoform X1

    See identical proteins and their annotated locations for XP_012923033.1

    UniProtKB/TrEMBL
    G5C7X8
    Conserved Domains (6) summary
    smart00139
    Location:835 → 989
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:694 → 794
    PH; Pleckstrin homology domain
    smart00295
    Location:1002 → 1233
    B41; Band 4.1 homologues
    cd13206
    Location:1229 → 1330
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:584 → 679
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    cl25732
    Location:65 → 202
    SMC_N; RecF/RecN/SMC N terminal domain

  2. XM_021247462.1 → XP_021103121.1  pleckstrin homology domain-containing family H member 1 isoform X1

    UniProtKB/TrEMBL
    G5C7X8
    Related
    ENSHGLP00000009264.1, ENSHGLT00000009364.1
    Conserved Domains (6) summary
    smart00139
    Location:835 → 989
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:694 → 794
    PH; Pleckstrin homology domain
    smart00295
    Location:1002 → 1233
    B41; Band 4.1 homologues
    cd13206
    Location:1229 → 1330
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:584 → 679
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    cl25732
    Location:65 → 202
    SMC_N; RecF/RecN/SMC N terminal domain

  3. XM_021247468.1 → XP_021103127.1  pleckstrin homology domain-containing family H member 1 isoform X2

    UniProtKB/TrEMBL
    A0AAX6S2F0
    Conserved Domains (6) summary
    smart00139
    Location:835 → 966
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:694 → 794
    PH; Pleckstrin homology domain
    smart00295
    Location:979 → 1210
    B41; Band 4.1 homologues
    cd13206
    Location:1206 → 1307
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:584 → 679
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    cl25732
    Location:65 → 202
    SMC_N; RecF/RecN/SMC N terminal domain

  4. XM_021247471.1 → XP_021103130.1  pleckstrin homology domain-containing family H member 1 isoform X3

    UniProtKB/TrEMBL
    A0AAX6S453
    Conserved Domains (5) summary
    smart00139
    Location:740 → 894
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:599 → 699
    PH; Pleckstrin homology domain
    smart00295
    Location:907 → 1138
    B41; Band 4.1 homologues
    cd13206
    Location:1134 → 1235
    FERM_C-lobe_PLEKHH1_PLEKHH2; FERM domain C-lobe of Pleckstrin homology domain-containing family H
    cd13282
    Location:489 → 584
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1

  5. XM_021247475.1 → XP_021103134.1  pleckstrin homology domain-containing family H member 1 isoform X4

    UniProtKB/TrEMBL
    A0AAX6S3B7
    Conserved Domains (5) summary
    smart00139
    Location:835 → 989
    MyTH4; Domain in Myosin and Kinesin Tails
    smart00233
    Location:694 → 794
    PH; Pleckstrin homology domain
    cd13282
    Location:584 → 679
    PH1_PLEKHH1_PLEKHH2; Pleckstrin homology (PH) domain containing, family H (with MyTH4 domain) members 1 and 2 (PLEKHH1) PH domain, repeat 1
    cl09511
    Location:1002 → 1073
    FERM_B-lobe; FERM domain B-lobe
    cl25732
    Location:65 → 202
    SMC_N; RecF/RecN/SMC N terminal domain

RNA

  1. XR_002390506.1 RNA Sequence

Nucleotide Protein
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