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Papln papilin, proteoglycan like sulfated glycoprotein [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101715641, updated on 1-Mar-2025

Summary

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Gene symbol
Papln
Gene description
papilin, proteoglycan like sulfated glycoprotein
See related
Ensembl:ENSHGLG00000013495 RGD:18909719
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Papln in Genome Data Viewer
Location:
chromosome: Un
Exon count:
30
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624734.1 (28142603..28174734, complement)

NW_004624734.1Genomic Context describing neighboring genes Neighboring gene NUMB endocytic adaptor protein Neighboring gene protein strawberry notch homolog 1-like Neighboring gene 60S ribosomal protein L30 pseudogene Neighboring gene presenilin 1 Neighboring gene nicotinamide phosphoribosyltransferase-like Neighboring gene RNA binding motif protein 25

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624734 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
papilin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624734.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    28142603..28174734 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021246668.1 → XP_021102327.1  papilin isoform X1

    UniProtKB/TrEMBL
    A0A0P6J6Q1, A0AAX6QNL6
    Conserved Domains (8) summary
    smart00209
    Location:29 → 80
    TSP1; Thrombospondin type 1 repeats
    smart00410
    Location:1167 → 1247
    IG_like; Immunoglobulin like
    pfam07679
    Location:1076 → 1147
    I-set; Immunoglobulin I-set domain
    pfam00014
    Location:780 → 832
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    pfam05986
    Location:185 → 298
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1263 → 1295
    PLAC; PLAC (protease and lacunin) domain
    pfam16626
    Location:841 → 924
    Papilin_u7; Linking region between Kunitz_BPTI and I-set on papilin
    cl28434
    Location:943 → 1021
    I-set; Immunoglobulin I-set domain

  2. XM_021246689.1 → XP_021102348.1  papilin isoform X3

    UniProtKB/TrEMBL
    A0A0P6J6Q1, A0AAX6S010
    Conserved Domains (8) summary
    smart00209
    Location:29 → 80
    TSP1; Thrombospondin type 1 repeats
    smart00410
    Location:1166 → 1246
    IG_like; Immunoglobulin like
    pfam07679
    Location:1076 → 1147
    I-set; Immunoglobulin I-set domain
    pfam00014
    Location:780 → 832
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    pfam05986
    Location:185 → 298
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1262 → 1294
    PLAC; PLAC (protease and lacunin) domain
    pfam16626
    Location:841 → 924
    Papilin_u7; Linking region between Kunitz_BPTI and I-set on papilin
    cl28434
    Location:943 → 1021
    I-set; Immunoglobulin I-set domain

  3. XM_013067393.2 → XP_012922847.1  papilin isoform X9

    UniProtKB/TrEMBL
    A0A0P6J6Q1, A0AAX6QKL3
    Conserved Domains (10) summary
    cd00096
    Location:1150 → 1216
    Ig; Immunoglobulin domain
    smart00408
    Location:1057 → 1116
    IGc2; Immunoglobulin C-2 Type
    smart00209
    Location:29 → 80
    TSP1; Thrombospondin type 1 repeats
    smart00410
    Location:1139 → 1219
    IG_like; Immunoglobulin like
    pfam07679
    Location:915 → 993
    I-set; Immunoglobulin I-set domain
    pfam00014
    Location:752 → 804
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    pfam05986
    Location:185 → 298
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1235 → 1267
    PLAC; PLAC (protease and lacunin) domain
    pfam16626
    Location:813 → 896
    Papilin_u7; Linking region between Kunitz_BPTI and I-set on papilin
    cl11960
    Location:914 → 977
    Ig; Immunoglobulin domain

  4. XM_013067389.2 → XP_012922843.1  papilin isoform X6

    UniProtKB/TrEMBL
    A0A0P6J6Q1, A0AAX6QPF9
    Conserved Domains (10) summary
    cd00096
    Location:1156 → 1222
    Ig; Immunoglobulin domain
    smart00408
    Location:1063 → 1122
    IGc2; Immunoglobulin C-2 Type
    smart00209
    Location:29 → 80
    TSP1; Thrombospondin type 1 repeats
    smart00410
    Location:1145 → 1225
    IG_like; Immunoglobulin like
    pfam07679
    Location:921 → 999
    I-set; Immunoglobulin I-set domain
    pfam00014
    Location:758 → 810
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    pfam05986
    Location:185 → 298
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1241 → 1273
    PLAC; PLAC (protease and lacunin) domain
    pfam16626
    Location:819 → 902
    Papilin_u7; Linking region between Kunitz_BPTI and I-set on papilin
    cl11960
    Location:920 → 983
    Ig; Immunoglobulin domain

  5. XM_021246700.1 → XP_021102359.1  papilin isoform X7

    UniProtKB/TrEMBL
    A0A0P6J6Q1, A0AAX6S1P9
    Conserved Domains (8) summary
    smart00209
    Location:29 → 80
    TSP1; Thrombospondin type 1 repeats
    smart00410
    Location:1126 → 1206
    IG_like; Immunoglobulin like
    pfam07679
    Location:1035 → 1106
    I-set; Immunoglobulin I-set domain
    pfam00014
    Location:739 → 791
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    pfam05986
    Location:185 → 298
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1222 → 1254
    PLAC; PLAC (protease and lacunin) domain
    pfam16626
    Location:800 → 883
    Papilin_u7; Linking region between Kunitz_BPTI and I-set on papilin
    cl28434
    Location:902 → 980
    I-set; Immunoglobulin I-set domain

  6. XM_013067384.2 → XP_012922838.1  papilin isoform X5

    UniProtKB/TrEMBL
    A0A0P6J6Q1, A0AAX6QPJ5
    Conserved Domains (10) summary
    cd00096
    Location:1164 → 1230
    Ig; Immunoglobulin domain
    smart00408
    Location:1071 → 1130
    IGc2; Immunoglobulin C-2 Type
    smart00209
    Location:29 → 80
    TSP1; Thrombospondin type 1 repeats
    smart00410
    Location:1153 → 1233
    IG_like; Immunoglobulin like
    pfam07679
    Location:929 → 1007
    I-set; Immunoglobulin I-set domain
    pfam00014
    Location:766 → 818
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    pfam05986
    Location:185 → 298
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1249 → 1281
    PLAC; PLAC (protease and lacunin) domain
    pfam16626
    Location:827 → 910
    Papilin_u7; Linking region between Kunitz_BPTI and I-set on papilin
    cl11960
    Location:928 → 991
    Ig; Immunoglobulin domain

  7. XM_013067382.2 → XP_012922836.1  papilin isoform X4

    UniProtKB/TrEMBL
    A0A0P6J6Q1, A0AAX6QL73
    Conserved Domains (10) summary
    cd00096
    Location:1172 → 1238
    Ig; Immunoglobulin domain
    smart00408
    Location:1079 → 1138
    IGc2; Immunoglobulin C-2 Type
    smart00209
    Location:29 → 80
    TSP1; Thrombospondin type 1 repeats
    smart00410
    Location:1161 → 1241
    IG_like; Immunoglobulin like
    pfam07679
    Location:937 → 1015
    I-set; Immunoglobulin I-set domain
    pfam00014
    Location:774 → 826
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    pfam05986
    Location:185 → 298
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1257 → 1289
    PLAC; PLAC (protease and lacunin) domain
    pfam16626
    Location:835 → 918
    Papilin_u7; Linking region between Kunitz_BPTI and I-set on papilin
    cl11960
    Location:936 → 999
    Ig; Immunoglobulin domain

  8. XM_021246682.1 → XP_021102341.1  papilin isoform X2

    UniProtKB/TrEMBL
    A0A0P6J6Q1, A0AAX6RYM6
    Conserved Domains (8) summary
    smart00209
    Location:29 → 80
    TSP1; Thrombospondin type 1 repeats
    smart00410
    Location:1167 → 1247
    IG_like; Immunoglobulin like
    pfam07679
    Location:1076 → 1147
    I-set; Immunoglobulin I-set domain
    pfam00014
    Location:780 → 832
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    pfam05986
    Location:185 → 298
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1262 → 1294
    PLAC; PLAC (protease and lacunin) domain
    pfam16626
    Location:841 → 924
    Papilin_u7; Linking region between Kunitz_BPTI and I-set on papilin
    cl28434
    Location:943 → 1021
    I-set; Immunoglobulin I-set domain

  9. XM_013067376.2 → XP_012922830.1  papilin isoform X1

    See identical proteins and their annotated locations for XP_012922830.1

    UniProtKB/TrEMBL
    A0A0P6J6Q1, A0AAX6QNL6
    Conserved Domains (8) summary
    smart00209
    Location:29 → 80
    TSP1; Thrombospondin type 1 repeats
    smart00410
    Location:1167 → 1247
    IG_like; Immunoglobulin like
    pfam07679
    Location:1076 → 1147
    I-set; Immunoglobulin I-set domain
    pfam00014
    Location:780 → 832
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    pfam05986
    Location:185 → 298
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1263 → 1295
    PLAC; PLAC (protease and lacunin) domain
    pfam16626
    Location:841 → 924
    Papilin_u7; Linking region between Kunitz_BPTI and I-set on papilin
    cl28434
    Location:943 → 1021
    I-set; Immunoglobulin I-set domain

  10. XM_021246674.1 → XP_021102333.1  papilin isoform X1

    UniProtKB/TrEMBL
    A0A0P6J6Q1, A0AAX6QNL6
    Conserved Domains (8) summary
    smart00209
    Location:29 → 80
    TSP1; Thrombospondin type 1 repeats
    smart00410
    Location:1167 → 1247
    IG_like; Immunoglobulin like
    pfam07679
    Location:1076 → 1147
    I-set; Immunoglobulin I-set domain
    pfam00014
    Location:780 → 832
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    pfam05986
    Location:185 → 298
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam08686
    Location:1263 → 1295
    PLAC; PLAC (protease and lacunin) domain
    pfam16626
    Location:841 → 924
    Papilin_u7; Linking region between Kunitz_BPTI and I-set on papilin
    cl28434
    Location:943 → 1021
    I-set; Immunoglobulin I-set domain

  11. XM_013067390.2 → XP_012922844.1  papilin isoform X8

    UniProtKB/TrEMBL
    A0A0P6J6Q1, A0AAX6QPA3
    Related
    ENSHGLP00000018835.1, ENSHGLT00000019023.1
    Conserved Domains (9) summary
    cd00096
    Location:1178 → 1244
    Ig; Immunoglobulin domain
    smart00408
    Location:1085 → 1144
    IGc2; Immunoglobulin C-2 Type
    smart00209
    Location:29 → 80
    TSP1; Thrombospondin type 1 repeats
    smart00410
    Location:1167 → 1247
    IG_like; Immunoglobulin like
    pfam07679
    Location:943 → 1021
    I-set; Immunoglobulin I-set domain
    pfam00014
    Location:780 → 832
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
    pfam05986
    Location:185 → 298
    ADAM_spacer1; ADAM-TS Spacer 1
    pfam16626
    Location:841 → 924
    Papilin_u7; Linking region between Kunitz_BPTI and I-set on papilin
    cl11960
    Location:942 → 1005
    Ig; Immunoglobulin domain
Nucleotide Protein
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