U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Terf2 telomeric repeat binding factor 2 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101713552, updated on 1-Mar-2025
Gene symbol
Terf2
Gene description
telomeric repeat binding factor 2
See related
Ensembl:ENSHGLG00000010709 RGD:18926707
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See Terf2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624746.1 (16992049..17020809)

NW_004624746.1Genomic Context describing neighboring genes Neighboring gene cytochrome b5 type B Neighboring gene translation machinery-associated protein 16 pseudogene Neighboring gene nucleolar pre-rRNA processing protein NIP7 Neighboring gene transmembrane p24 trafficking protein 6 Neighboring gene component of oligomeric golgi complex 8 Neighboring gene peptide deformylase, mitochondrial

Genomic Sequence:
NW_004624746 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G-rich strand telomeric DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded telomeric DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomerase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of telomere maintenance via recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of telomeric D-loop disassembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protection from non-homologous end joining at telomere IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to chromosome, telomeric region IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of telomere maintenance via telomerase IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomeric D-loop disassembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomeric loop formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome, telomeric region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of shelterin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
telomeric repeat-binding factor 2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624746.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    16992049..17020809
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004842943.3 → XP_004843000.2  telomeric repeat-binding factor 2

    UniProtKB/TrEMBL
    A0AAX6P3W0, G5AK43
    Related
    ENSHGLP00000014967.1, ENSHGLT00000015117.1
    Conserved Domains (4) summary
    smart00717
    Location:485 → 534
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd11660
    Location:486 → 534
    SANT_TRF; Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family
    cd00280
    Location:87 → 286
    TRFH; Telomeric Repeat binding Factor or TTAGGG Repeat binding Factor, central (dimerization) domain Homology; TRFH. Telomeres are protein/DNA complexes that make up the physical ends of eukaryotic linear chromosomes and are essential for chromosome stability, ...
    pfam16772
    Location:318 → 358
    TERF2_RBM; Telomeric repeat-binding factor 2 Rap1-binding motif
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases