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Sema4c semaphorin 4C [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101713072, updated on 1-Mar-2025
Gene symbol
Sema4c
Gene description
semaphorin 4C
See related
Ensembl:ENSHGLG00000013625 RGD:18914538
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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See Sema4c in Genome Data Viewer
Location:
chromosome: Un
Exon count:
16
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624749.1 (2737251..2747540, complement)

NW_004624749.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 23 Neighboring gene ankyrin repeat domain 39 Neighboring gene family with sequence similarity 178 member B Neighboring gene uncharacterized LOC110349055 Neighboring gene cytochrome c oxidase subunit 5B, mitochondrial

Genomic Sequence:
NW_004624749 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chemorepellent activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables semaphorin receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in muscle cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of axon extension involved in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neural crest cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in semaphorin-plexin signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
semaphorin-4C

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624749.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    2737251..2747540 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013072152.2 → XP_012927606.1  semaphorin-4C isoform X2

    See identical proteins and their annotated locations for XP_012927606.1

    UniProtKB/TrEMBL
    A0AAX6QVE8, G5BMU6
    Conserved Domains (4) summary
    cd11258
    Location:42 → 498
    Sema_4C; The Sema domain, a protein interacting module, of semaphorin 4C (Sema4C)
    smart00410
    Location:562 → 627
    IG_like; Immunoglobulin like
    smart00423
    Location:500 → 528
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl11960
    Location:563 → 647
    Ig; Immunoglobulin domain

  2. XM_013072151.2 → XP_012927605.1  semaphorin-4C isoform X2

    See identical proteins and their annotated locations for XP_012927605.1

    UniProtKB/TrEMBL
    A0AAX6QVE8, G5BMU6
    Conserved Domains (4) summary
    cd11258
    Location:42 → 498
    Sema_4C; The Sema domain, a protein interacting module, of semaphorin 4C (Sema4C)
    smart00410
    Location:562 → 627
    IG_like; Immunoglobulin like
    smart00423
    Location:500 → 528
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl11960
    Location:563 → 647
    Ig; Immunoglobulin domain

  3. XM_004844388.3 → XP_004844445.1  semaphorin-4C isoform X1

    UniProtKB/TrEMBL
    A0AAX6P6C0, G5BMU6
    Related
    ENSHGLP00000019018.1, ENSHGLT00000019207.1
    Conserved Domains (4) summary
    cd11258
    Location:65 → 521
    Sema_4C; The Sema domain, a protein interacting module, of semaphorin 4C (Sema4C)
    smart00410
    Location:585 → 650
    IG_like; Immunoglobulin like
    smart00423
    Location:523 → 551
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl11960
    Location:586 → 670
    Ig; Immunoglobulin domain

  4. XM_013072153.2 → XP_012927607.1  semaphorin-4C isoform X3

    UniProtKB/TrEMBL
    A0AAX6QVH9, G5BMU6
    Conserved Domains (4) summary
    cd11258
    Location:65 → 521
    Sema_4C; The Sema domain, a protein interacting module, of semaphorin 4C (Sema4C)
    smart00410
    Location:585 → 650
    IG_like; Immunoglobulin like
    smart00423
    Location:523 → 551
    PSI; domain found in Plexins, Semaphorins and Integrins
    cl11960
    Location:586 → 670
    Ig; Immunoglobulin domain
Nucleotide Protein
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