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Tfr2 transferrin receptor 2 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101712680, updated on 1-Mar-2025
Gene symbol
Tfr2
Gene description
transferrin receptor 2
See related
Ensembl:ENSHGLG00000011682 RGD:18900080
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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See Tfr2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624740.1 (16451520..16469393)

NW_004624740.1Genomic Context describing neighboring genes Neighboring gene G protein subunit beta 2 Neighboring gene actin like 6B Neighboring gene motile sperm domain containing 3 Neighboring gene procollagen C-endopeptidase enhancer

Genomic Sequence:
NW_004624740 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transferrin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endocytic iron import into cell IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transferrin transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
transferrin receptor protein 2

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624740.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    16451520..16469393
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021254498.1 → XP_021110157.1  transferrin receptor protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6SKG8
    Conserved Domains (3) summary
    cd09848
    Location:408 → 651
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:210 → 395
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:683 → 802
    TFR_dimer; Transferrin receptor-like dimerisation domain

  2. XM_004840183.3 → XP_004840240.1  transferrin receptor protein 2 isoform X1

    See identical proteins and their annotated locations for XP_004840240.1

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6NZC5
    Conserved Domains (3) summary
    cd09848
    Location:417 → 660
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:219 → 404
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:692 → 815
    TFR_dimer; Transferrin receptor-like dimerization domain

  3. XM_013070535.2 → XP_012925989.1  transferrin receptor protein 2 isoform X2

    See identical proteins and their annotated locations for XP_012925989.1

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6NZD8
    Conserved Domains (3) summary
    cd09848
    Location:409 → 652
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:211 → 396
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:684 → 803
    TFR_dimer; Transferrin receptor-like dimerisation domain

  4. XM_013070536.2 → XP_012925990.1  transferrin receptor protein 2 isoform X3

    See identical proteins and their annotated locations for XP_012925990.1

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6SKG8
    Conserved Domains (3) summary
    cd09848
    Location:408 → 651
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:210 → 395
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:683 → 802
    TFR_dimer; Transferrin receptor-like dimerisation domain

  5. XM_004840182.3 → XP_004840239.1  transferrin receptor protein 2 isoform X1

    See identical proteins and their annotated locations for XP_004840239.1

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6NZC5
    Conserved Domains (3) summary
    cd09848
    Location:417 → 660
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:219 → 404
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:692 → 815
    TFR_dimer; Transferrin receptor-like dimerization domain

  6. XM_013070538.2 → XP_012925992.1  transferrin receptor protein 2 isoform X6

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6QV21
    Conserved Domains (3) summary
    cd09848
    Location:394 → 637
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    pfam04253
    Location:669 → 792
    TFR_dimer; Transferrin receptor-like dimerization domain
    cl10459
    Location:219 → 381
    Peptidases_S8_S53; Peptidase domain in the S8 and S53 families

  7. XM_004840186.3 → XP_004840243.1  transferrin receptor protein 2 isoform X2

    See identical proteins and their annotated locations for XP_004840243.1

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6NZD8
    Conserved Domains (3) summary
    cd09848
    Location:409 → 652
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:211 → 396
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:684 → 803
    TFR_dimer; Transferrin receptor-like dimerisation domain

  8. XM_004840188.3 → XP_004840245.1  transferrin receptor protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6NZ35
    Conserved Domains (3) summary
    cd09848
    Location:417 → 650
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:219 → 404
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:682 → 805
    TFR_dimer; Transferrin receptor-like dimerization domain

  9. XM_004840187.3 → XP_004840244.1  transferrin receptor protein 2 isoform X3

    See identical proteins and their annotated locations for XP_004840244.1

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6SKG8
    Conserved Domains (3) summary
    cd09848
    Location:408 → 651
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:210 → 395
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:683 → 802
    TFR_dimer; Transferrin receptor-like dimerisation domain

  10. XM_021254500.1 → XP_021110159.1  transferrin receptor protein 2 isoform X7

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6SNG5
    Conserved Domains (3) summary
    cd09848
    Location:267 → 510
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:69 → 254
    PA_TfR; Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 family. ...
    pfam04253
    Location:542 → 661
    TFR_dimer; Transferrin receptor-like dimerisation domain

  11. XM_004840184.3 → XP_004840241.1  transferrin receptor protein 2 isoform X1

    See identical proteins and their annotated locations for XP_004840241.1

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6NZC5
    Conserved Domains (3) summary
    cd09848
    Location:417 → 660
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:219 → 404
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:692 → 815
    TFR_dimer; Transferrin receptor-like dimerization domain

  12. XM_021254496.1 → XP_021110155.1  transferrin receptor protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6NZD8
    Conserved Domains (3) summary
    cd09848
    Location:409 → 652
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:211 → 396
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:684 → 803
    TFR_dimer; Transferrin receptor-like dimerisation domain

  13. XM_021254499.1 → XP_021110158.1  transferrin receptor protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6SKG8
    Conserved Domains (3) summary
    cd09848
    Location:408 → 651
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:210 → 395
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:683 → 802
    TFR_dimer; Transferrin receptor-like dimerisation domain

  14. XM_013070537.2 → XP_012925991.1  transferrin receptor protein 2 isoform X3

    See identical proteins and their annotated locations for XP_012925991.1

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6SKG8
    Conserved Domains (3) summary
    cd09848
    Location:408 → 651
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:210 → 395
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:683 → 802
    TFR_dimer; Transferrin receptor-like dimerisation domain

  15. XM_004840185.3 → XP_004840242.1  transferrin receptor protein 2 isoform X1

    See identical proteins and their annotated locations for XP_004840242.1

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6NZC5
    Conserved Domains (3) summary
    cd09848
    Location:417 → 660
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:219 → 404
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:692 → 815
    TFR_dimer; Transferrin receptor-like dimerization domain

  16. XM_021254497.1 → XP_021110156.1  transferrin receptor protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6NZD8
    Conserved Domains (3) summary
    cd09848
    Location:409 → 652
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:211 → 396
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:684 → 803
    TFR_dimer; Transferrin receptor-like dimerisation domain

  17. XM_004840189.3 → XP_004840246.1  transferrin receptor protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A0P6J998, A0AAX6NZE7
    Related
    ENSHGLP00000016297.1, ENSHGLT00000016466.1
    Conserved Domains (3) summary
    cd09848
    Location:409 → 642
    M28_TfR; M28 Zn-peptidase Transferrin Receptor family
    cd02128
    Location:211 → 396
    PA_TfR; PA_TfR: Protease-associated domain containing proteins like transferrin receptor (TfR). This group contains various PA domain-containing proteins similar to human TfR1 and TfR2. TfR1 and TfR2 are type II membrane proteins, belonging to the peptidase M28 ...
    pfam04253
    Location:674 → 797
    TFR_dimer; Transferrin receptor-like dimerization domain
Nucleotide Protein
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