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Usp2 ubiquitin specific peptidase 2 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101712304, updated on 8-Mar-2024

Summary

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Gene symbol
Usp2
Gene description
ubiquitin specific peptidase 2
Locus tag
GW7_18691
See related
Ensembl:ENSHGLG00000014829
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624784.1 (14729762..14755982, complement)

NW_004624784.1Genomic Context describing neighboring genes Neighboring gene C1q and TNF related 5 Neighboring gene membrane frizzled-related protein Neighboring gene nibrin-like Neighboring gene Thy-1 cell surface antigen

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624784 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ubiquitin carboxyl-terminal hydrolase 2
Names
Ubiquitin carboxyl-terminal hydrolase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624784.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    14729762..14755982 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013076659.2 → XP_012932113.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X2

    Conserved Domains (2) summary
    cl02553
    Location:275 → 506
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
    pfam00443
    Location:273 → 507
    UCH; Ubiquitin carboxyl-terminal hydrolase

  2. XM_004856800.3 → XP_004856857.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

    See identical proteins and their annotated locations for XP_004856857.1

    UniProtKB/TrEMBL
    G5BHP7
    Conserved Domains (1) summary
    pfam00443
    Location:274 → 603
    UCH; Ubiquitin carboxyl-terminal hydrolase

  3. XM_021237734.1 → XP_021093393.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

    UniProtKB/TrEMBL
    G5BHP7
    Related
    ENSHGLP00000020728.1, ENSHGLT00000020931.1
    Conserved Domains (1) summary
    pfam00443
    Location:274 → 603
    UCH; Ubiquitin carboxyl-terminal hydrolase

  4. XM_004856802.2 → XP_004856859.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

    See identical proteins and their annotated locations for XP_004856859.1

    UniProtKB/TrEMBL
    G5BHP7
    Conserved Domains (1) summary
    pfam00443
    Location:274 → 603
    UCH; Ubiquitin carboxyl-terminal hydrolase

  5. XM_004856801.3 → XP_004856858.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X1

    See identical proteins and their annotated locations for XP_004856858.1

    UniProtKB/TrEMBL
    G5BHP7
    Conserved Domains (1) summary
    pfam00443
    Location:274 → 603
    UCH; Ubiquitin carboxyl-terminal hydrolase

  6. XM_004856803.2 → XP_004856860.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X4

    Related
    ENSHGLP00000020729.1, ENSHGLT00000020932.1
    Conserved Domains (2) summary
    cd02674
    Location:59 → 388
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam00443
    Location:57 → 387
    UCH; Ubiquitin carboxyl-terminal hydrolase

  7. XM_013076660.2 → XP_012932114.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X5

    Conserved Domains (2) summary
    cd02674
    Location:37 → 366
    Peptidase_C19R; A subfamily of peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    pfam00443
    Location:35 → 365
    UCH; Ubiquitin carboxyl-terminal hydrolase

  8. XM_021237735.1 → XP_021093394.1  ubiquitin carboxyl-terminal hydrolase 2 isoform X3

    Conserved Domains (1) summary
    pfam00443
    Location:274 → 508
    UCH; Ubiquitin carboxyl-terminal hydrolase
Nucleotide Protein
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