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Bcar1 BCAR1 scaffold protein, Cas family member [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101709701, updated on 1-Mar-2025
Gene symbol
Bcar1
Gene description
BCAR1 scaffold protein, Cas family member
See related
Ensembl:ENSHGLG00000017063 RGD:18921421
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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See Bcar1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
8
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624746.1 (11660859..11695991)

NW_004624746.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 170A Neighboring gene uncharacterized protein C7orf73-like Neighboring gene craniofacial development protein 1 Neighboring gene chymotrypsinogen B-like Neighboring gene uncharacterized LOC110348765

Genomic Sequence:
NW_004624746 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
breast cancer anti-estrogen resistance protein 1
Names
BCAR1, Cas family scaffold protein
BCAR1, Cas family scaffolding protein

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624746.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    11660859..11695991
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013071485.2 → XP_012926939.1  breast cancer anti-estrogen resistance protein 1 isoform X2

    UniProtKB/TrEMBL
    A0AAX6QWG3, G5B5X8
    Related
    ENSHGLP00000023935.1, ENSHGLT00000024153.1
    Conserved Domains (3) summary
    cd11552
    Location:461 → 616
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:5 → 71
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    pfam12026
    Location:662 → 871
    DUF3513; Domain of unknown function (DUF3513)

  2. XM_004842838.2 → XP_004842895.1  breast cancer anti-estrogen resistance protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A0P6JHG4, G5B5X8
    Related
    ENSHGLP00000023936.1, ENSHGLT00000024154.1
    Conserved Domains (3) summary
    cd11552
    Location:461 → 616
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:4 → 71
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    pfam12026
    Location:662 → 871
    DUF3513; Domain of unknown function (DUF3513)

  3. XM_004842839.2 → XP_004842896.1  breast cancer anti-estrogen resistance protein 1 isoform X3

    UniProtKB/TrEMBL
    A0AAX6P3R1, G5B5X8
    Conserved Domains (4) summary
    cd11552
    Location:407 → 562
    Serine_rich_BCAR1; Serine rich Four helix bundle domain of CAS (Crk-Associated Substrate) scaffolding protein, Breast Cancer Anti-estrogen Resistance 1; a protein interaction module
    cd12001
    Location:4 → 71
    SH3_BCAR1; Src homology 3 domain of the CAS (Crk-Associated Substrate) scaffolding protein family member, Breast Cancer Anti-estrogen Resistance 1
    pfam07223
    Location:100 → 284
    DUF1421; Protein of unknown function (DUF1421)
    pfam12026
    Location:608 → 817
    DUF3513; Domain of unknown function (DUF3513)
Nucleotide Protein
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