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Syne2 spectrin repeat containing nuclear envelope protein 2 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101709558, updated on 8-Mar-2024

Summary

Gene symbol
Syne2
Gene description
spectrin repeat containing nuclear envelope protein 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
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Genomic context

See Syne2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
119
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624734.1 (36832490..37167438, complement)

NW_004624734.1Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein G pseudogene Neighboring gene uncharacterized LOC110346514 Neighboring gene estrogen receptor 2 Neighboring gene uncharacterized LOC110346529 Neighboring gene ras-related protein Rab-2A pseudogene Neighboring gene N-alpha-acetyltransferase 50 pseudogene Neighboring gene 60S ribosomal protein L35a pseudogene

Genomic regions, transcripts, and products

Genomic Sequence:
NW_004624734 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

General protein information

Preferred Names
nesprin-2
Names
spectrin repeat containing, nuclear envelope 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624734.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    36832490..37167438 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013067744.2XP_012923198.1  nesprin-2 isoform X1

    UniProtKB/TrEMBL
    G5BCZ7
    Conserved Domains (5) summary
    COG5069
    Location:28278
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:60656275
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam10541
    Location:68106839
    KASH; Nuclear envelope localization domain
    cl25732
    Location:51185969
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:6351084
    Neuromodulin_N; Gap junction protein N-terminal region
  2. XM_021247769.1XP_021103428.1  nesprin-2 isoform X1

    UniProtKB/TrEMBL
    G5BCZ7
    Conserved Domains (5) summary
    COG5069
    Location:28278
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:60656275
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam10541
    Location:68106839
    KASH; Nuclear envelope localization domain
    cl25732
    Location:51185969
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:6351084
    Neuromodulin_N; Gap junction protein N-terminal region
  3. XM_021247775.1XP_021103434.1  nesprin-2 isoform X3

    UniProtKB/TrEMBL
    G5BCZ7
    Conserved Domains (3) summary
    cd00176
    Location:51555365
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam10541
    Location:59005929
    KASH; Nuclear envelope localization domain
    cl25732
    Location:42085059
    SMC_N; RecF/RecN/SMC N terminal domain
  4. XM_013067754.2XP_012923208.1  nesprin-2 isoform X4

    UniProtKB/TrEMBL
    G5BCZ7
    Conserved Domains (6) summary
    TIGR00618
    Location:7431412
    sbcc; exonuclease SbcC
    COG1196
    Location:16212322
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00176
    Location:50735283
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    TIGR02168
    Location:12151929
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam10541
    Location:58185847
    KASH; Nuclear envelope localization domain
    cl02488
    Location:45334743
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
  5. XM_013067755.2XP_012923209.1  nesprin-2 isoform X5

    Conserved Domains (2) summary
    cd00176
    Location:131341
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam10541
    Location:876905
    KASH; Nuclear envelope localization domain
  6. XM_021247781.1XP_021103440.1  nesprin-2 isoform X6

    Conserved Domains (2) summary
    cd00176
    Location:15225
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam10541
    Location:760789
    KASH; Nuclear envelope localization domain
  7. XM_021247771.1XP_021103430.1  nesprin-2 isoform X2

    UniProtKB/TrEMBL
    G5BCZ7
    Conserved Domains (5) summary
    COG5069
    Location:28278
    SAC6; Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) [Cytoskeleton]
    cd00176
    Location:60656275
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam10541
    Location:67876816
    KASH; Nuclear envelope localization domain
    cl25732
    Location:51185969
    SMC_N; RecF/RecN/SMC N terminal domain
    cl26511
    Location:6351084
    Neuromodulin_N; Gap junction protein N-terminal region