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Esr2 estrogen receptor 2 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101708704, updated on 19-Jun-2024

Summary

Gene symbol
Esr2
Gene description
estrogen receptor 2
See related
Ensembl:ENSHGLG00000010137
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
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Genomic context

See Esr2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
14
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624734.1 (36742913..36862993)

NW_004624734.1Genomic Context describing neighboring genes Neighboring gene small nuclear ribonucleoprotein G pseudogene Neighboring gene uncharacterized LOC110346514 Neighboring gene spectrin repeat containing nuclear envelope protein 2 Neighboring gene uncharacterized LOC110346529 Neighboring gene ras-related protein Rab-2A pseudogene

Genomic regions, transcripts, and products

Genomic Sequence:
NW_004624734 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nuclear estrogen receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables nuclear receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables steroid binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to estradiol stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in estrogen receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624734.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    36742913..36862993
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021247796.1XP_021103455.1  estrogen receptor beta isoform X4

    Conserved Domains (3) summary
    cd07171
    Location:163244
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam12497
    Location:31141
    ERbeta_N; Estrogen receptor beta
    cl11397
    Location:282447
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
  2. XM_021247798.1XP_021103457.1  estrogen receptor beta isoform X5

    Conserved Domains (3) summary
    cd07171
    Location:163244
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam12497
    Location:31141
    ERbeta_N; Estrogen receptor beta
    cl11397
    Location:282427
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
  3. XM_021247789.1XP_021103448.1  estrogen receptor beta isoform X3

    UniProtKB/TrEMBL
    G5BCZ8
    Conserved Domains (3) summary
    cd07171
    Location:163244
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam12497
    Location:31141
    ERbeta_N; Estrogen receptor beta
    cl11397
    Location:282506
    NR_LBD; The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators
  4. XM_004837415.2XP_004837472.1  estrogen receptor beta isoform X1

    UniProtKB/TrEMBL
    G5BCZ8
    Conserved Domains (3) summary
    cd06949
    Location:282535
    NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
    cd07171
    Location:163244
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam12497
    Location:31141
    ERbeta_N; Estrogen receptor beta
  5. XM_004837416.2XP_004837473.1  estrogen receptor beta isoform X2

    UniProtKB/TrEMBL
    A0A0P6IZY0, G5BCZ8
    Related
    ENSHGLP00000014187.1, ENSHGLT00000014330.1
    Conserved Domains (3) summary
    cd06949
    Location:282517
    NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
    cd07171
    Location:163244
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam12497
    Location:35141
    ERbeta_N; Estrogen receptor beta
  6. XM_021247785.1XP_021103444.1  estrogen receptor beta isoform X1

    UniProtKB/TrEMBL
    G5BCZ8
    Related
    ENSHGLP00000014186.1, ENSHGLT00000014329.1
    Conserved Domains (3) summary
    cd06949
    Location:282535
    NR_LBD_ER; Ligand binding domain of Estrogen receptor, which are activated by the hormone 17beta-estradiol (estrogen)
    cd07171
    Location:163244
    NR_DBD_ER; DNA-binding domain of estrogen receptors (ER) is composed of two C4-type zinc fingers
    pfam12497
    Location:31141
    ERbeta_N; Estrogen receptor beta