U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101707800, updated on 1-Mar-2025
Gene symbol
Map4k4
Gene description
mitogen-activated protein kinase kinase kinase kinase 4
See related
Ensembl:ENSHGLG00000010571 RGD:18923213
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table
See Map4k4 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
34
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624749.1 (6332686..6495942)

NW_004624749.1Genomic Context describing neighboring genes Neighboring gene peptide chain release factor 1-like, mitochondrial pseudogene Neighboring gene regulatory factor X8 Neighboring gene S-phase kinase-associated protein 1-like Neighboring gene uncharacterized LOC110349063 Neighboring gene TELO2-interacting protein 1 homolog pseudogene Neighboring gene twinfilin-2 pseudogene

Genomic Sequence:
NW_004624749 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
mitogen-activated protein kinase kinase kinase kinase 4

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624749.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    6332686..6495942
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013072143.2 → XP_012927597.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X7

    UniProtKB/TrEMBL
    A0AAX6QXG0, G5C8V8
    Conserved Domains (3) summary
    smart00036
    Location:1004 → 1302
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:25 → 289
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:8 → 289
    PKc_like; Protein Kinases, catalytic domain

  2. XM_004844455.2 → XP_004844512.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X11

    UniProtKB/TrEMBL
    A0AAX6P5T4, G5C8V8
    Related
    ENSHGLP00000014811.1, ENSHGLT00000014956.1
    Conserved Domains (3) summary
    smart00036
    Location:973 → 1271
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:25 → 289
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:8 → 289
    PKc_like; Protein Kinases, catalytic domain

  3. XM_021258113.1 → XP_021113772.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X2

    UniProtKB/TrEMBL
    A0AAX6SVD7, G5C8V8
    Conserved Domains (2) summary
    smart00036
    Location:1067 → 1365
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cl21453
    Location:8 → 289
    PKc_like; Protein Kinases, catalytic domain

  4. XM_021258118.1 → XP_021113777.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X15

    UniProtKB/TrEMBL
    A0AAX6SWP3, G5C8V8
    Conserved Domains (2) summary
    smart00036
    Location:922 → 1220
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06636
    Location:8 → 289
    STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

  5. XM_004844460.2 → XP_004844517.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X18

    UniProtKB/TrEMBL
    A0AAX6P5Q9, G5C8V8
    Conserved Domains (3) summary
    smart00036
    Location:895 → 1193
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:25 → 289
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06636
    Location:8 → 289
    STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

  6. XM_004844457.2 → XP_004844514.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X16

    UniProtKB/TrEMBL
    A0AAX6P6E1, G5C8V8
    Conserved Domains (3) summary
    smart00036
    Location:919 → 1217
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:25 → 289
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:8 → 289
    PKc_like; Protein Kinases, catalytic domain

  7. XM_013072139.2 → XP_012927593.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X1

    UniProtKB/TrEMBL
    A0AAX6QWN5, G5C8V8
    Conserved Domains (3) summary
    smart00036
    Location:1068 → 1366
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:25 → 289
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:8 → 289
    PKc_like; Protein Kinases, catalytic domain

  8. XM_013072140.2 → XP_012927594.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X3

    UniProtKB/TrEMBL
    A0AAX6QYB9, G5C8V8
    Conserved Domains (3) summary
    smart00036
    Location:1065 → 1363
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:25 → 289
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:8 → 289
    PKc_like; Protein Kinases, catalytic domain

  9. XM_021258115.1 → XP_021113774.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X9

    UniProtKB/TrEMBL
    A0AAX6SZC7, G5C8V8
    Conserved Domains (2) summary
    smart00036
    Location:989 → 1287
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06636
    Location:8 → 289
    STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

  10. XM_013072141.2 → XP_012927595.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X4

    UniProtKB/TrEMBL
    A0AAX6QTM7, G5C8V8
    Related
    ENSHGLP00000014809.1, ENSHGLT00000014954.1
    Conserved Domains (3) summary
    smart00036
    Location:1037 → 1335
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:25 → 289
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:8 → 289
    PKc_like; Protein Kinases, catalytic domain

  11. XM_004844461.2 → XP_004844518.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X19

    UniProtKB/TrEMBL
    A0AAX6P6B8, G5C8V8
    Related
    ENSHGLP00000014808.1, ENSHGLT00000014953.1
    Conserved Domains (3) summary
    smart00036
    Location:892 → 1190
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:25 → 289
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06636
    Location:8 → 289
    STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

  12. XM_021258119.1 → XP_021113778.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X20

    UniProtKB/TrEMBL
    A0AAX6SYD7
    Conserved Domains (2) summary
    smart00036
    Location:840 → 1138
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06636
    Location:8 → 289
    STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

  13. XM_013072145.2 → XP_012927599.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X8

    UniProtKB/TrEMBL
    A0AAX6QWE4, G5C8V8
    Conserved Domains (3) summary
    smart00036
    Location:990 → 1288
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:25 → 289
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06636
    Location:8 → 289
    STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

  14. XM_013072142.2 → XP_012927596.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X5

    UniProtKB/TrEMBL
    A0AAX6QSS9, G5C8V8
    Conserved Domains (3) summary
    smart00036
    Location:1014 → 1312
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:25 → 289
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:8 → 289
    PKc_like; Protein Kinases, catalytic domain

  15. XM_021258116.1 → XP_021113775.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X10

    UniProtKB/TrEMBL
    A0AAX6SX55, G5C8V8
    Related
    ENSHGLP00000014810.1, ENSHGLT00000014955.1
    Conserved Domains (2) summary
    smart00036
    Location:983 → 1281
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cl21453
    Location:8 → 289
    PKc_like; Protein Kinases, catalytic domain

  16. XM_013072146.2 → XP_012927600.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X13

    UniProtKB/TrEMBL
    A0AAX6QTN3, G5C8V8
    Conserved Domains (3) summary
    smart00036
    Location:936 → 1234
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:25 → 289
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06636
    Location:8 → 289
    STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

  17. XM_021258117.1 → XP_021113776.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X14

    UniProtKB/TrEMBL
    A0AAX6SVF3, G5C8V8
    Conserved Domains (2) summary
    smart00036
    Location:935 → 1233
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cd06636
    Location:8 → 289
    STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

  18. XM_004844456.2 → XP_004844513.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X12

    UniProtKB/TrEMBL
    A0A0P6J1M1, G5C8V8
    Related
    ENSHGLP00000014807.1, ENSHGLT00000014952.1
    Conserved Domains (3) summary
    smart00036
    Location:956 → 1254
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:25 → 289
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06636
    Location:8 → 289
    STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

  19. XM_004844459.2 → XP_004844516.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X17

    UniProtKB/TrEMBL
    A0AAX6P5N2, G5C8V8
    Related
    ENSHGLP00000014812.1, ENSHGLT00000014957.1
    Conserved Domains (3) summary
    smart00036
    Location:905 → 1203
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:25 → 289
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06636
    Location:8 → 289
    STKc_MAP4K4_6_N; N-terminal Catalytic domain of the Serine/Threonine Kinases, Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 and 6

  20. XM_021258114.1 → XP_021113773.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X6

    UniProtKB/TrEMBL
    A0AAX6T1C8, G5C8V8
    Conserved Domains (2) summary
    smart00036
    Location:1009 → 1307
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cl21453
    Location:2 → 230
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases