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Pard6a par-6 family cell polarity regulator alpha [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101707435, updated on 1-Mar-2025
Gene symbol
Pard6a
Gene description
par-6 family cell polarity regulator alpha
Locus tag
GW7_02364
See related
Ensembl:ENSHGLG00000018571 RGD:18916937
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
all
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See Pard6a in Genome Data Viewer
Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624746.1 (18686916..18688739, complement)

NW_004624746.1Genomic Context describing neighboring genes Neighboring gene Gfo/Idh/MocA-like oxidoreductase domain containing 2 Neighboring gene chromosome unknown C16orf86 homolog Neighboring gene enkurin domain containing 1 Neighboring gene capping protein regulator and myosin 1 linker 2 Neighboring gene ACD shelterin complex subunit and telomerase recruitment factor Neighboring gene CCCTC-binding factor Neighboring gene uncharacterized LOC106009246

Genomic Sequence:
NW_004624746 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein kinase C binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in centrosome cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment or maintenance of cell polarity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cellular localization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
partitioning defective 6 homolog alpha
Names
Partitioning defective 6-like protein alpha
par-6 partitioning defective 6 homolog alpha

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624746.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    18686916..18688739 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004843020.2 → XP_004843077.1  partitioning defective 6 homolog alpha isoform X2

    UniProtKB/TrEMBL
    A0A0P6JIJ0
    Conserved Domains (2) summary
    cd06403
    Location:16 → 95
    PB1_Par6; The PB1 domain is an essential part of Par6 protein which in complex with Par3 and aPKC proteins is crucial for establishment of apical-basal polarity of animal cells. The PB1 domain is a modular domain mediating specific protein-protein interactions ...
    cd00992
    Location:155 → 246
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  2. XM_004843019.2 → XP_004843076.1  partitioning defective 6 homolog alpha isoform X1

    See identical proteins and their annotated locations for XP_004843076.1

    UniProtKB/TrEMBL
    G5C668
    Related
    ENSHGLP00000026090.1, ENSHGLT00000026321.1
    Conserved Domains (2) summary
    cd06403
    Location:16 → 95
    PB1_Par6; The PB1 domain is an essential part of Par6 protein which in complex with Par3 and aPKC proteins is crucial for establishment of apical-basal polarity of animal cells. The PB1 domain is a modular domain mediating specific protein-protein interactions ...
    cd00992
    Location:156 → 247
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
Nucleotide Protein
Heading Accession and Version

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