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Psd4 pleckstrin and Sec7 domain containing 4 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101706961, updated on 1-Mar-2025
Gene symbol
Psd4
Gene description
pleckstrin and Sec7 domain containing 4
See related
Ensembl:ENSHGLG00000016761 RGD:18917049
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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See Psd4 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624749.1 (13250146..13288672)

NW_004624749.1Genomic Context describing neighboring genes Neighboring gene interleukin 1 family member 10 Neighboring gene interleukin 1 receptor antagonist Neighboring gene proliferating cell nuclear antigen-like Neighboring gene paired box 8 Neighboring gene uncharacterized LOC110349080

Genomic Sequence:
NW_004624749 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phospholipid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of ARF protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in ruffle membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
PH and SEC7 domain-containing protein 4

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624749.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    13250146..13288672
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021258177.1 → XP_021113836.1  PH and SEC7 domain-containing protein 4 isoform X2

    UniProtKB/TrEMBL
    A0AAX6SVL8, G5B413
    Conserved Domains (3) summary
    cd00171
    Location:463 → 632
    Sec7; Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor ...
    cl17171
    Location:666 → 752
    PH-like; Pleckstrin homology-like domain
    cl25751
    Location:152 → 470
    DUF4045; Domain of unknown function (DUF4045)

  2. XM_021258174.1 → XP_021113833.1  PH and SEC7 domain-containing protein 4 isoform X1

    UniProtKB/TrEMBL
    A0AAX6P6I7, G5B413
    Related
    ENSHGLP00000023503.1, ENSHGLT00000023720.1
    Conserved Domains (3) summary
    cd00171
    Location:463 → 632
    Sec7; Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor ...
    cd13295
    Location:666 → 793
    PH_EFA6; Exchange Factor for ARF6 Pleckstrin homology (PH) domain
    cl25751
    Location:152 → 470
    DUF4045; Domain of unknown function (DUF4045)

  3. XM_004844537.2 → XP_004844594.1  PH and SEC7 domain-containing protein 4 isoform X1

    See identical proteins and their annotated locations for XP_004844594.1

    UniProtKB/TrEMBL
    A0AAX6P6I7, G5B413
    Conserved Domains (3) summary
    cd00171
    Location:463 → 632
    Sec7; Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor ...
    cd13295
    Location:666 → 793
    PH_EFA6; Exchange Factor for ARF6 Pleckstrin homology (PH) domain
    cl25751
    Location:152 → 470
    DUF4045; Domain of unknown function (DUF4045)

  4. XM_021258175.1 → XP_021113834.1  PH and SEC7 domain-containing protein 4 isoform X1

    UniProtKB/TrEMBL
    A0AAX6P6I7, G5B413
    Conserved Domains (3) summary
    cd00171
    Location:463 → 632
    Sec7; Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor ...
    cd13295
    Location:666 → 793
    PH_EFA6; Exchange Factor for ARF6 Pleckstrin homology (PH) domain
    cl25751
    Location:152 → 470
    DUF4045; Domain of unknown function (DUF4045)

  5. XM_021258176.1 → XP_021113835.1  PH and SEC7 domain-containing protein 4 isoform X1

    UniProtKB/TrEMBL
    A0AAX6P6I7, G5B413
    Conserved Domains (3) summary
    cd00171
    Location:463 → 632
    Sec7; Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor ...
    cd13295
    Location:666 → 793
    PH_EFA6; Exchange Factor for ARF6 Pleckstrin homology (PH) domain
    cl25751
    Location:152 → 470
    DUF4045; Domain of unknown function (DUF4045)

  6. XM_004844539.3 → XP_004844596.1  PH and SEC7 domain-containing protein 4 isoform X1

    See identical proteins and their annotated locations for XP_004844596.1

    UniProtKB/TrEMBL
    A0AAX6P6I7, G5B413
    Conserved Domains (3) summary
    cd00171
    Location:463 → 632
    Sec7; Sec7 domain; Domain named after the S. cerevisiae SEC7 gene product. The Sec7 domain is the central domain of the guanine-nucleotide-exchange factors (GEFs) of the ADP-ribosylation factor family of small GTPases (ARFs) . It carries the exchange factor ...
    cd13295
    Location:666 → 793
    PH_EFA6; Exchange Factor for ARF6 Pleckstrin homology (PH) domain
    cl25751
    Location:152 → 470
    DUF4045; Domain of unknown function (DUF4045)
Nucleotide Protein
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