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Slc12a3 solute carrier family 12 member 3 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101704301, updated on 1-Mar-2025
Gene symbol
Slc12a3
Gene description
solute carrier family 12 member 3
Locus tag
GW7_14912
See related
Ensembl:ENSHGLG00000011157 RGD:18929300
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Location:
chromosome: Un
Exon count:
30
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624746.1 (29087867..29132793, complement)

NW_004624746.1Genomic Context describing neighboring genes Neighboring gene cholesteryl ester transfer protein Neighboring gene homocysteine inducible ER protein with ubiquitin like domain 1 Neighboring gene nucleoporin 93

Genomic Sequence:
NW_004624746 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables sodium:potassium:chloride symporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell volume homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chloride ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chloride transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in potassium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in potassium ion import across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sodium ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
solute carrier family 12 member 3
Names
solute carrier family 12 (sodium/chloride transporters), member 3

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624746.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    29087867..29132793 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013071627.2 → XP_012927081.1  solute carrier family 12 member 3 isoform X7

    UniProtKB/TrEMBL
    A0AAX6QVE2
    Conserved Domains (3) summary
    TIGR00930
    Location:59 → 984
    2a30; K-Cl cotransporter
    pfam03522
    Location:655 → 984
    SLC12; Solute carrier family 12
    pfam08403
    Location:45 → 115
    AA_permease_N; Amino acid permease N-terminal

  2. XM_004843195.3 → XP_004843252.1  solute carrier family 12 member 3 isoform X4

    UniProtKB/TrEMBL
    A0A0P6JW96
    Conserved Domains (3) summary
    TIGR00930
    Location:59 → 1028
    2a30; K-Cl cotransporter
    pfam03522
    Location:654 → 1028
    SLC12; Solute carrier family 12
    pfam08403
    Location:45 → 114
    AA_permease_N; Amino acid permease N-terminal

  3. XM_004843194.3 → XP_004843251.1  solute carrier family 12 member 3 isoform X3

    See identical proteins and their annotated locations for XP_004843251.1

    UniProtKB/TrEMBL
    G5BR76
    Related
    ENSHGLP00000015591.1, ENSHGLT00000015755.1
    Conserved Domains (3) summary
    TIGR00930
    Location:59 → 1029
    2a30; K-Cl cotransporter
    pfam03522
    Location:655 → 1029
    SLC12; Solute carrier family 12
    pfam08403
    Location:45 → 115
    AA_permease_N; Amino acid permease N-terminal

  4. XM_013071625.2 → XP_012927079.1  solute carrier family 12 member 3 isoform X5

    UniProtKB/TrEMBL
    A0AAX6QUM5
    Conserved Domains (3) summary
    TIGR00930
    Location:59 → 998
    2a30; K-Cl cotransporter
    pfam03522
    Location:655 → 991
    SLC12; Solute carrier family 12
    pfam08403
    Location:45 → 115
    AA_permease_N; Amino acid permease N-terminal

  5. XM_013071624.2 → XP_012927078.1  solute carrier family 12 member 3 isoform X2

    UniProtKB/TrEMBL
    A0AAX6QTU8
    Conserved Domains (3) summary
    TIGR00930
    Location:59 → 1003
    2a30; K-Cl cotransporter
    pfam03522
    Location:654 → 983
    SLC12; Solute carrier family 12
    pfam08403
    Location:45 → 114
    AA_permease_N; Amino acid permease N-terminal

  6. XM_013071626.2 → XP_012927080.1  solute carrier family 12 member 3 isoform X6

    UniProtKB/TrEMBL
    A0AAX6QUQ7
    Conserved Domains (3) summary
    TIGR00930
    Location:59 → 986
    2a30; K-Cl cotransporter
    pfam03522
    Location:637 → 966
    SLC12; Solute carrier family 12
    pfam08403
    Location:45 → 115
    AA_permease_N; Amino acid permease N-terminal

  7. XM_013071623.2 → XP_012927077.1  solute carrier family 12 member 3 isoform X1

    UniProtKB/TrEMBL
    A0AAX6QSY7
    Conserved Domains (3) summary
    TIGR00930
    Location:59 → 1004
    2a30; K-Cl cotransporter
    pfam03522
    Location:655 → 984
    SLC12; Solute carrier family 12
    pfam08403
    Location:45 → 115
    AA_permease_N; Amino acid permease N-terminal

RNA

  1. XR_002394372.1 RNA Sequence

  2. XR_002394374.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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