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Ctsh cathepsin H [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101700582, updated on 8-Mar-2024

Summary

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Gene symbol
Ctsh
Gene description
cathepsin H
Locus tag
GW7_10432
See related
Ensembl:ENSHGLG00000000119
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Ctsh in Genome Data Viewer
Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624941.1 (82209..98156, complement)

NW_004624941.1Genomic Context describing neighboring genes Neighboring gene cyclin-Y-like protein 1 Neighboring gene mortality factor 4 like 1 Neighboring gene Ras protein specific guanine nucleotide releasing factor 1 Neighboring gene SRA stem-loop-interacting RNA-binding protein, mitochondrial-like Neighboring gene ankyrin repeat domain 34C

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624941 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pro-cathepsin H
Names
pro-cathepsin H preproprotein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624941.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    82209..98156 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004874804.2 → XP_004874861.1  pro-cathepsin H isoform X1

    See identical proteins and their annotated locations for XP_004874861.1

    UniProtKB/TrEMBL
    G5B3N9
    Related
    ENSHGLP00000000096.1, ENSHGLT00000000125.1
    Conserved Domains (3) summary
    PTZ00203
    Location:1 → 331
    PTZ00203; cathepsin L protease; Provisional
    pfam00112
    Location:116 → 331
    Peptidase_C1; Papain family cysteine protease
    pfam08246
    Location:34 → 89
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)

  2. XM_021252182.1 → XP_021107841.1  pro-cathepsin H isoform X3

    Conserved Domains (1) summary
    pfam00112
    Location:45 → 260
    Peptidase_C1; Papain family cysteine protease

  3. XM_013069274.2 → XP_012924728.1  pro-cathepsin H isoform X2

    Conserved Domains (2) summary
    pfam00112
    Location:116 → 275
    Peptidase_C1; Papain family cysteine protease
    pfam08246
    Location:34 → 89
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
Nucleotide Protein
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