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Myrf myelin regulatory factor [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101699599, updated on 1-Mar-2025

Summary

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Gene symbol
Myrf
Gene description
myelin regulatory factor
See related
Ensembl:ENSHGLG00000003384 RGD:18928596
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Genomic context

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See Myrf in Genome Data Viewer
Location:
chromosome: Un
Exon count:
29
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624926.1 (615991..636167, complement)

NW_004624926.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110347394 Neighboring gene flap structure-specific endonuclease 1 Neighboring gene transmembrane protein 258 Neighboring gene diacylglycerol lipase alpha Neighboring gene uncharacterized LOC110347404

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_004624926 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in central nervous system myelin maintenance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein autoprocessing IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
myelin regulatory factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624926.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    615991..636167 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004874311.3 → XP_004874368.1  myelin regulatory factor isoform X8

    UniProtKB/TrEMBL
    A0AAX6QHI4, G5AYF7
    Related
    ENSHGLP00000004622.1, ENSHGLT00000004684.1
    Conserved Domains (4) summary
    pfam05224
    Location:377 → 524
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:571 → 631
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:651 → 686
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:986 → 1115
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2

  2. XM_013069110.2 → XP_012924564.1  myelin regulatory factor isoform X4

    UniProtKB/TrEMBL
    A0AAX6QSL9, G5AYF7
    Related
    ENSHGLP00000004623.1, ENSHGLT00000004685.1
    Conserved Domains (4) summary
    pfam05224
    Location:422 → 569
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:616 → 676
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:696 → 731
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:991 → 1120
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2

  3. XM_021251824.1 → XP_021107483.1  myelin regulatory factor isoform X3

    UniProtKB/TrEMBL
    A0AAX6SG42, G5AYF7
    Conserved Domains (5) summary
    pfam05224
    Location:426 → 573
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:620 → 680
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:700 → 735
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:993 → 1122
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2
    cl26464
    Location:55 → 363
    Atrophin-1; Atrophin-1 family

  4. XM_021251823.1 → XP_021107482.1  myelin regulatory factor isoform X2

    UniProtKB/TrEMBL
    A0AAX6SHG5, G5AYF7
    Conserved Domains (5) summary
    pfam05224
    Location:426 → 573
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:620 → 680
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:700 → 735
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:994 → 1123
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2
    cl26464
    Location:55 → 363
    Atrophin-1; Atrophin-1 family

  5. XM_013069109.2 → XP_012924563.1  myelin regulatory factor isoform X1

    UniProtKB/TrEMBL
    A0AAX6QN05, G5AYF7
    Conserved Domains (4) summary
    pfam05224
    Location:426 → 573
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:620 → 680
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:700 → 735
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:995 → 1124
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2

  6. XM_021251825.1 → XP_021107484.1  myelin regulatory factor isoform X5

    UniProtKB/TrEMBL
    A0AAX6SFH6, G5AYF7
    Conserved Domains (5) summary
    pfam05224
    Location:403 → 550
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:597 → 657
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:677 → 712
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    pfam13888
    Location:972 → 1101
    MRF_C2; Myelin gene regulatory factor C-terminal domain 2
    cl26464
    Location:55 → 340
    Atrophin-1; Atrophin-1 family

  7. XM_021251827.1 → XP_021107486.1  myelin regulatory factor isoform X7

    UniProtKB/TrEMBL
    A0AAX6SDJ5
    Conserved Domains (4) summary
    pfam05224
    Location:426 → 573
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:620 → 680
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:700 → 735
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    cl26464
    Location:55 → 363
    Atrophin-1; Atrophin-1 family

  8. XM_021251826.1 → XP_021107485.1  myelin regulatory factor isoform X6

    UniProtKB/TrEMBL
    A0AAX6SI25
    Conserved Domains (4) summary
    pfam05224
    Location:426 → 573
    NDT80_PhoG; NDT80 / PhoG like DNA-binding family
    pfam13884
    Location:620 → 680
    Peptidase_S74; Chaperone of endosialidase
    pfam13887
    Location:700 → 735
    MRF_C1; Myelin gene regulatory factor -C-terminal domain 1
    cl26464
    Location:55 → 363
    Atrophin-1; Atrophin-1 family

RNA

  1. XR_002392019.1 RNA Sequence

Nucleotide Protein
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