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LOC101698541 disintegrin and metalloproteinase domain-containing protein 21 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101698541, updated on 1-Mar-2025
Gene symbol
LOC101698541
Gene description
disintegrin and metalloproteinase domain-containing protein 21
See related
Ensembl:ENSHGLG00000021282 RGD:18936617
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Also known as
Adam21
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See LOC101698541 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624734.1 (30698749..30706603)

NW_004624734.1Genomic Context describing neighboring genes Neighboring gene disintegrin and metalloproteinase domain-containing protein 20-like Neighboring gene spermatogenesis-associated serine-rich protein 2 pseudogene Neighboring gene uncharacterized LOC110346354 Neighboring gene polypyrimidine tract-binding protein 3-like Neighboring gene synaptojanin 2 binding protein

Genomic Sequence:
NW_004624734 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in male gonad development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in sperm head plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
disintegrin and metalloproteinase domain-containing protein 21
Names
ADAM metallopeptidase domain 21
disintegrin and metalloproteinase domain-containing protein 21 preproprotein

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624734.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    30698749..30706603
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021247136.1 → XP_021102795.1  disintegrin and metalloproteinase domain-containing protein 21

    UniProtKB/TrEMBL
    A0A0P6JKK8, A0AAX6RYE9
    Conserved Domains (4) summary
    smart00608
    Location:492 → 628
    ACR; ADAM Cysteine-Rich Domain
    cd04269
    Location:208 → 397
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
    pfam00200
    Location:416 → 488
    Disintegrin; Disintegrin
    pfam01562
    Location:41 → 159
    Pep_M12B_propep; Reprolysin family propeptide

  2. XM_004837296.3 → XP_004837353.2  disintegrin and metalloproteinase domain-containing protein 21

    UniProtKB/TrEMBL
    A0A0P6JKK8, A0AAX6RYE9
    Conserved Domains (4) summary
    smart00608
    Location:492 → 628
    ACR; ADAM Cysteine-Rich Domain
    cd04269
    Location:208 → 397
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
    pfam00200
    Location:416 → 488
    Disintegrin; Disintegrin
    pfam01562
    Location:41 → 159
    Pep_M12B_propep; Reprolysin family propeptide

  3. XM_021247133.1 → XP_021102792.1  disintegrin and metalloproteinase domain-containing protein 21

    UniProtKB/TrEMBL
    A0A0P6JKK8, A0AAX6RYE9
    Related
    ENSHGLP00000028872.1, ENSHGLT00000029492.1
    Conserved Domains (4) summary
    smart00608
    Location:492 → 628
    ACR; ADAM Cysteine-Rich Domain
    cd04269
    Location:208 → 397
    ZnMc_adamalysin_II_like; Zinc-dependent metalloprotease; adamalysin_II_like subfamily. Adamalysin II is a snake venom zinc endopeptidase. This subfamily contains other snake venom metalloproteinases, as well as membrane-anchored metalloproteases belonging to the ADAM family. ...
    pfam00200
    Location:416 → 488
    Disintegrin; Disintegrin
    pfam01562
    Location:41 → 159
    Pep_M12B_propep; Reprolysin family propeptide
Nucleotide Protein
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