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Rfc2 replication factor C subunit 2 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101697046, updated on 1-Mar-2025
Gene symbol
Rfc2
Gene description
replication factor C subunit 2
Locus tag
GW7_08909
See related
Ensembl:ENSHGLG00000012236 RGD:18914867
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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See Rfc2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624740.1 (13737225..13748876)

NW_004624740.1Genomic Context describing neighboring genes Neighboring gene CAP-Gly domain containing linker protein 2 Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC101725474 Neighboring gene linker for activation of T cells family member 2 Neighboring gene eukaryotic translation initiation factor 4H Neighboring gene LIM domain kinase 1

Genomic Sequence:
NW_004624740 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Kim EB, et al. Nature, 2011 Oct 12. PMID 21993625, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA clamp loader activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA-templated DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of DNA replication factor C complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
replication factor C subunit 2

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624740.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    13737225..13748876
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021254363.1 → XP_021110022.1  replication factor C subunit 2 isoform X4

    UniProtKB/TrEMBL
    A0AAX6SK49
    Conserved Domains (1) summary
    cl25702
    Location:34 → 277
    Rad17; Rad17 cell cycle checkpoint protein

  2. XM_004840035.3 → XP_004840092.1  replication factor C subunit 2 isoform X1

    See identical proteins and their annotated locations for XP_004840092.1

    UniProtKB/TrEMBL
    G5BG91
    Related
    ENSHGLP00000017090.1, ENSHGLT00000017261.1
    Conserved Domains (4) summary
    cd00009
    Location:49 → 183
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    PLN03025
    Location:34 → 346
    PLN03025; replication factor C subunit; Provisional
    pfam08542
    Location:272 → 340
    Rep_fac_C; Replication factor C C-terminal domain
    pfam16193
    Location:206 → 234
    AAA_assoc_2; AAA C-terminal domain

  3. XM_021254362.1 → XP_021110021.1  replication factor C subunit 2 isoform X2

    UniProtKB/TrEMBL
    A0AAX6SKP6
    Conserved Domains (1) summary
    cl25702
    Location:34 → 319
    Rad17; Rad17 cell cycle checkpoint protein

  4. XM_004840036.3 → XP_004840093.1  replication factor C subunit 2 isoform X3

    UniProtKB/TrEMBL
    A0AAX6NZ48
    Conserved Domains (4) summary
    cd00009
    Location:49 → 183
    AAA; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
    PLN03025
    Location:34 → 308
    PLN03025; replication factor C subunit; Provisional
    pfam08542
    Location:260 → 302
    Rep_fac_C; Replication factor C C-terminal domain
    pfam16193
    Location:206 → 234
    AAA_assoc_2; AAA C-terminal domain
Nucleotide Protein
Heading Accession and Version

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