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LOC101696702 histone-lysine N-methyltransferase SETDB2 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101696702, updated on 1-Mar-2025
Gene symbol
LOC101696702
Gene description
histone-lysine N-methyltransferase SETDB2
See related
Ensembl:ENSHGLG00000003303 RGD:18913752
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Also known as
Phf11; Setdb2
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Try the new Transcripts and proteins table
See LOC101696702 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624748.1 (5147938..5238034, complement)

NW_004624748.1Genomic Context describing neighboring genes Neighboring gene ARF like GTPase 11 Neighboring gene RCC1 and BTB domain containing protein 1 Neighboring gene pre-mRNA-splicing factor SPF27 pseudogene Neighboring gene calcium binding protein 39 like Neighboring gene type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase pseudogene Neighboring gene cytidine and dCMP deaminase domain containing 1

Genomic Sequence:
NW_004624748 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables histone H3K9 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables histone binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in heterochromatin organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of gene expression IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
PHD finger protein 11; histone-lysine N-methyltransferase SETDB2
Names
SET domain bifurcated 2

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624748.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    5147938..5238034 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004844157.3XP_004844214.1  PHD finger protein 11 isoform X1

    UniProtKB/TrEMBL
    A0A0P6J9H4, G5B9Z1
    Related
    ENSHGLP00000004514.1, ENSHGLT00000004576.1
    Conserved Domains (1) summary
    cl22851
    Location:50164
    PHD_SF; PHD finger superfamily
  2. XM_004844164.3XP_004844221.2  histone-lysine N-methyltransferase SETDB2 isoform X2

    UniProtKB/TrEMBL
    A0AAX6P5I8
    Conserved Domains (4) summary
    smart00317
    Location:621680
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    cd01395
    Location:159219
    HMT_MBD; Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated ...
    pfam05033
    Location:241354
    Pre-SET; Pre-SET motif
    cl22851
    Location:707821
    PHD_SF; PHD finger superfamily