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Nfatc3 nuclear factor of activated T cells 3 [ Heterocephalus glaber (naked mole-rat) ]

Gene ID: 101696341, updated on 1-Mar-2025
Gene symbol
Nfatc3
Gene description
nuclear factor of activated T cells 3
Locus tag
GW7_02383
See related
Ensembl:ENSHGLG00000013248 RGD:18935672
Gene type
protein coding
RefSeq status
MODEL
Organism
Heterocephalus glaber
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
Orthologs
human mouse all
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Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624746.1 (18083051..18210399, complement)

NW_004624746.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110348782 Neighboring gene phospholipase A2 group XV Neighboring gene epithelial splicing regulatory protein 2 Neighboring gene non-histone chromosomal protein HMG-17 pseudogene Neighboring gene actin-related protein 3 pseudogene Neighboring gene dihydrouridine synthase 2 Neighboring gene presequence translocase associated motor 16 Neighboring gene BAG family molecular chaperone regulator 5

Genomic Sequence:
NW_004624746 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in calcineurin-NFAT signaling cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
nuclear factor of activated T-cells, cytoplasmic 3
Names
Nuclear factor of activated T-cells, cytoplasmic 3

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RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HetGla_female_1.0 Primary Assembly

Genomic

  1. NW_004624746.1 Reference HetGla_female_1.0 Primary Assembly

    Range
    18083051..18210399 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021256811.1 → XP_021112470.1  nuclear factor of activated T-cells, cytoplasmic 3 isoform X1

    UniProtKB/TrEMBL
    A0AAX6STH3
    Conserved Domains (2) summary
    cd07881
    Location:423 → 596
    RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
    cd01178
    Location:601 → 701
    IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

  2. XM_021256812.1 → XP_021112471.1  nuclear factor of activated T-cells, cytoplasmic 3 isoform X2

    UniProtKB/TrEMBL
    A0AAX6SS00
    Conserved Domains (2) summary
    cd07881
    Location:423 → 596
    RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
    cd01178
    Location:601 → 701
    IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

  3. XM_004842985.2 → XP_004843042.1  nuclear factor of activated T-cells, cytoplasmic 3 isoform X3

    UniProtKB/TrEMBL
    A0AAX6P410
    Related
    ENSHGLP00000018509.1, ENSHGLT00000018693.1
    Conserved Domains (2) summary
    cd07881
    Location:423 → 596
    RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
    cd01178
    Location:601 → 701
    IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.

  4. XM_013071534.2 → XP_012926988.1  nuclear factor of activated T-cells, cytoplasmic 3 isoform X4

    See identical proteins and their annotated locations for XP_012926988.1

    UniProtKB/TrEMBL
    G5C687
    Related
    ENSHGLP00000018508.1, ENSHGLT00000018692.1
    Conserved Domains (2) summary
    cd07881
    Location:423 → 596
    RHD-n_NFAT; N-terminal sub-domain of the Rel homology domain (RHD) of nuclear factor of activated T-cells (NFAT) proteins
    cd01178
    Location:601 → 701
    IPT_NFAT; IPT domain of the NFAT family of transcription factors. NFAT transcription complexes are a target of calcineurin, a calcium dependent phosphatase, and activate genes mainly involved in cell-cell-interaction.
Nucleotide Protein
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