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IL1B interleukin 1 beta [ Mustela putorius furo (domestic ferret) ]

Gene ID: 101688006, updated on 16-Nov-2023

Summary

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Gene symbol
IL1B
Gene description
interleukin 1 beta
See related
Ensembl:ENSMPUG00000010784
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mustela putorius furo (sub-species: furo)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Mustela
Also known as
IL-1beta
Orthologs
human mouse all
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Genomic context

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See IL1B in Genome Data Viewer
Location:
chromosome: Un
Exon count:
7
Annotation release Status Assembly Chr Location
102 current ASM1176430v1.1 (GCF_011764305.1) Unplaced Scaffold NW_025421343.1 (16475007..16482336)
101 previous assembly MusPutFur1.0 (GCF_000215625.1) Unplaced Scaffold NW_004570549.1 (2361..5465)

NW_025421343.1Genomic Context describing neighboring genes Neighboring gene interleukin-36 beta Neighboring gene interleukin-36 gamma Neighboring gene interleukin 1 alpha Neighboring gene cytoskeleton associated protein 2 like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. IL-21 and other serum proinflammatory cytokine levels in patients with multiple myeloma at diagnosis. Mehtap O, et al. J Postgrad Med, 2014 Apr-Jun. PMID 24823512
  2. Molecular cloning and phylogenetic analysis of inflammatory cytokines of the ferret (Mustela putorius furo). Nakata M, et al. J Vet Med Sci, 2008 Jun. PMID 18628593
  3. TaqMan real time RT-PCR assays for detecting ferret innate and adaptive immune responses. Carolan LA, et al. J Virol Methods, 2014 Sep 1. PMID 24797460, Free PMC Article
  4. De-novo transcriptome sequencing of a normalized cDNA pool from influenza infected ferrets. Camp JV, et al. PLoS One, 2012. PMID 22606336, Free PMC Article
  5. Sequencing, annotation, and characterization of the influenza ferret infectome. León AJ, et al. J Virol, 2013 Feb. PMID 23236062, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. IL-1beta was significantly elevated in advanced stage patients (stage II-III) (P 0.040).
    Title: IL-21 and other serum proinflammatory cytokine levels in patients with multiple myeloma at diagnosis.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables interleukin-1 receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to lipopolysaccharide IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of immature T cell proliferation in thymus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of nitric-oxide synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-1 beta
Names
IL-1 beta
interleukin-1beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310200.1 → NP_001297129.1  interleukin-1 beta precursor

    See identical proteins and their annotated locations for NP_001297129.1

    Status: PROVISIONAL

    Source sequence(s)
    AB301555
    UniProtKB/Swiss-Prot
    A4UYK8
    UniProtKB/TrEMBL
    A0A8U0V1T4, G9K5K2
    Conserved Domains (2) summary
    smart00125
    Location:122 → 267
    IL1; Interleukin-1 homologues
    pfam02394
    Location:1 → 104
    IL1_propep; Interleukin-1 propeptide

RefSeqs of Annotated Genomes: Mustela putorius furo Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1176430v1.1 Primary Assembly

Genomic

  1. NW_025421343.1 Reference ASM1176430v1.1 Primary Assembly

    Range
    16475007..16482336
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045078949.1 → XP_044934884.1  interleukin-1 beta isoform X1

    UniProtKB/Swiss-Prot
    A4UYK8
    UniProtKB/TrEMBL
    A0A8U0V1T4, G9K5K2
    Conserved Domains (2) summary
    smart00125
    Location:122 → 267
    IL1; Interleukin-1 homologues
    pfam02394
    Location:1 → 104
    IL1_propep; Interleukin-1 propeptide
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A4UYK8.1 GenPept UniProtKB/Swiss-Prot:A4UYK8

Gene LinkOut

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