U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MECOM MDS1 and EVI1 complex locus [ Orcinus orca (killer whale) ]

Gene ID: 101289893, updated on 8-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
MECOM
Gene description
MDS1 and EVI1 complex locus
See related
EnsemblRapid:ENSOORG00010001247
Gene type
protein coding
RefSeq status
MODEL
Organism
Orcinus orca
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Delphinidae; Orcinus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: 5
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_02 current mOrcOrc1.1 (GCF_937001465.1) 5 NC_064563.1 (52195532..52763836, complement)

Chromosome 5 - NC_064563.1Genomic Context describing neighboring genes Neighboring gene nucleotide triphosphate diphosphatase NUDT15-like Neighboring gene uncharacterized LOC117201598 Neighboring gene transfer RNA valine (anticodon AAC) Neighboring gene actin related protein T3

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_064563.1 Chromosome 5 Reference mOrcOrc1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription activator activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone H3K9 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
histone-lysine N-methyltransferase MECOM

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_937001465.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mOrcOrc1.1 Primary Assembly

Genomic

  1. NC_064563.1 Reference mOrcOrc1.1 Primary Assembly

    Range
    52195532..52763836 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012533299.3 → XP_012388753.2  histone-lysine N-methyltransferase MECOM isoform X10

    Conserved Domains (3) summary
    COG5048
    Location:289 → 729
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:590 → 610
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd19214
    Location:47 → 204
    PR-SET_PRDM3; PR-SET domain found in MDS1 and EVI1 complex locus protein and similar proteins

  2. XM_033429566.2 → XP_033285457.1  histone-lysine N-methyltransferase MECOM isoform X4

    Related
    ENSOORP00010001069.1, ENSOORT00010001618.1
    Conserved Domains (6) summary
    PHA00733
    Location:845 → 964
    PHA00733; hypothetical protein
    COG5189
    Location:302 → 395
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:914 → 934
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd19214
    Location:47 → 204
    PR-SET_PRDM3; PR-SET domain found in MDS1 and EVI1 complex locus protein and similar proteins
    pfam00096
    Location:912 → 934
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:926 → 950
    zf-H2C2_2; Zinc-finger double domain

  3. XM_004270573.4 → XP_004270621.1  histone-lysine N-methyltransferase MECOM isoform X2

    Related
    ENSOORP00010001068.1, ENSOORT00010001617.1
    Conserved Domains (5) summary
    smart00317
    Location:80 → 196
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
    sd00017
    Location:923 → 943
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:921 → 943
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:935 → 959
    zf-H2C2_2; Zinc-finger double domain
    pfam15909
    Location:351 → 432
    zf-C2H2_8; C2H2-type zinc ribbon

  4. XM_033429567.2 → XP_033285458.1  histone-lysine N-methyltransferase MECOM isoform X5

    Conserved Domains (6) summary
    PHA00733
    Location:878 → 974
    PHA00733; hypothetical protein
    COG5189
    Location:344 → 396
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:924 → 944
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd19214
    Location:47 → 204
    PR-SET_PRDM3; PR-SET domain found in MDS1 and EVI1 complex locus protein and similar proteins
    pfam00096
    Location:922 → 944
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:936 → 960
    zf-H2C2_2; Zinc-finger double domain

  5. XM_033429564.2 → XP_033285455.1  histone-lysine N-methyltransferase MECOM isoform X1

    Conserved Domains (6) summary
    PHA00733
    Location:878 → 974
    PHA00733; hypothetical protein
    COG5189
    Location:344 → 396
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:924 → 944
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd19214
    Location:47 → 204
    PR-SET_PRDM3; PR-SET domain found in MDS1 and EVI1 complex locus protein and similar proteins
    pfam00096
    Location:922 → 944
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:936 → 960
    zf-H2C2_2; Zinc-finger double domain

  6. XM_033429565.2 → XP_033285456.1  histone-lysine N-methyltransferase MECOM isoform X3

    Conserved Domains (6) summary
    PHA00733
    Location:846 → 965
    PHA00733; hypothetical protein
    COG5189
    Location:344 → 396
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:915 → 935
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd19214
    Location:47 → 204
    PR-SET_PRDM3; PR-SET domain found in MDS1 and EVI1 complex locus protein and similar proteins
    pfam00096
    Location:913 → 935
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:927 → 951
    zf-H2C2_2; Zinc-finger double domain

  7. XM_012533298.3 → XP_012388752.2  histone-lysine N-methyltransferase MECOM isoform X9

    Conserved Domains (5) summary
    COG5048
    Location:289 → 641
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:600 → 620
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd19214
    Location:47 → 204
    PR-SET_PRDM3; PR-SET domain found in MDS1 and EVI1 complex locus protein and similar proteins
    pfam00096
    Location:598 → 620
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:612 → 636
    zf-H2C2_2; Zinc-finger double domain

  8. XM_033429569.2 → XP_033285460.1  histone-lysine N-methyltransferase MECOM isoform X6

    Conserved Domains (5) summary
    PHA00733
    Location:690 → 786
    PHA00733; hypothetical protein
    sd00017
    Location:736 → 756
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl40432
    Location:1 → 16
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
    pfam00096
    Location:734 → 756
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:748 → 772
    zf-H2C2_2; Zinc-finger double domain

  9. XM_033429574.2 → XP_033285465.1  histone-lysine N-methyltransferase MECOM isoform X6

    Related
    ENSOORP00010001067.1, ENSOORT00010001616.1
    Conserved Domains (5) summary
    PHA00733
    Location:690 → 786
    PHA00733; hypothetical protein
    sd00017
    Location:736 → 756
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl40432
    Location:1 → 16
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
    pfam00096
    Location:734 → 756
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:748 → 772
    zf-H2C2_2; Zinc-finger double domain

  10. XM_033429573.2 → XP_033285464.1  histone-lysine N-methyltransferase MECOM isoform X8

    Conserved Domains (6) summary
    PHA00733
    Location:657 → 776
    PHA00733; hypothetical protein
    sd00017
    Location:726 → 746
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl40432
    Location:1 → 16
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
    pfam00096
    Location:724 → 746
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:738 → 762
    zf-H2C2_2; Zinc-finger double domain
    cd20908
    Location:136 → 178
    SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins

  11. XM_004270575.4 → XP_004270623.1  histone-lysine N-methyltransferase MECOM isoform X7

    See identical proteins and their annotated locations for XP_004270623.1

    Conserved Domains (6) summary
    PHA00733
    Location:689 → 785
    PHA00733; hypothetical protein
    sd00017
    Location:735 → 755
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cl40432
    Location:1 → 16
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
    pfam00096
    Location:733 → 755
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:747 → 771
    zf-H2C2_2; Zinc-finger double domain
    cd20908
    Location:136 → 178
    SUF4-like; N-terminal domain of Oryza sativa transcription factor SUPPRESSOR OF FRI 4 (OsSUF4), Arabidopsis thaliana SUF4 (AtSUF4), and similar proteins
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.