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SCN5A sodium voltage-gated channel alpha subunit 5 [ Gorilla gorilla gorilla (western lowland gorilla) ]

Gene ID: 101149930, updated on 3-Apr-2024

Summary

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Gene symbol
SCN5A
Gene description
sodium voltage-gated channel alpha subunit 5
See related
Ensembl:ENSGGOG00000012938
Gene type
protein coding
RefSeq status
MODEL
Organism
Gorilla gorilla gorilla (sub-species: gorilla)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Gorilla
Orthologs
human mouse all
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Genomic context

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See SCN5A in Genome Data Viewer
Location:
chromosome: 2
Exon count:
29
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mGorGor1-v2.0_pri (GCF_029281585.2) 2 NC_086017.1 (48448265..48550757, complement)
RS_2023_04 previous assembly NHGRI_mGorGor1-v1.1-0.2.freeze_pri (GCF_029281585.1) 3 NC_073227.1 (48547725..48649525, complement)

Chromosome 2 - NC_086017.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein eL20-like Neighboring gene exo/endonuclease G Neighboring gene sodium voltage-gated channel alpha subunit 10 Neighboring gene sodium voltage-gated channel alpha subunit 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables voltage-gated sodium channel activity involved in cardiac muscle cell action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane depolarization during action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuronal action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of atrial cardiac muscle cell membrane depolarization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of heart rate IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of voltage-gated sodium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sodium channel protein type 5 subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029281585.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

Genomic

  1. NC_086017.1 Reference NHGRI_mGorGor1-v2.0_pri Primary Assembly

    Range
    48448265..48550757 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019024737.4 → XP_018880282.1  sodium channel protein type 5 subunit alpha isoform X7

    UniProtKB/TrEMBL
    A0A2I2YCL7, G3RB05
    Related
    ENSGGOP00000012641.3
    Conserved Domains (5) summary
    cd13433
    Location:1471 → 1523
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1204 → 1479
    Ion_trans; Ion transport protein
    pfam06512
    Location:953 → 1200
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:485 → 667
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1794 → 1841
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

  2. XM_019024739.4 → XP_018880284.1  sodium channel protein type 5 subunit alpha isoform X3

    UniProtKB/TrEMBL
    G3RB05
    Conserved Domains (5) summary
    cd13433
    Location:1470 → 1522
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1203 → 1478
    Ion_trans; Ion transport protein
    pfam06512
    Location:953 → 1199
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:485 → 667
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1793 → 1840
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

  3. XM_063703705.1 → XP_063559775.1  sodium channel protein type 5 subunit alpha isoform X6

  4. XM_055381296.2 → XP_055237271.1  sodium channel protein type 5 subunit alpha isoform X4

  5. XM_063703704.1 → XP_063559774.1  sodium channel protein type 5 subunit alpha isoform X5

  6. XM_055381294.2 → XP_055237269.1  sodium channel protein type 5 subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A2I2Z2C6

  7. XM_055381295.2 → XP_055237270.1  sodium channel protein type 5 subunit alpha isoform X2

Nucleotide Protein
Heading Accession and Version

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