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FRZB frizzled related protein [ Ovis aries (sheep) ]

Gene ID: 101118419, updated on 8-Aug-2026
Gene symbol
FRZB
Gene description
frizzled related protein
See related
Ensembl:ENSOARG00020047372
Gene type
protein coding
RefSeq status
MODEL
Organism
Ovis aries
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Ovis
Orthologs
all
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See FRZB in Genome Data Viewer
Location:
chromosome: 2
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2023_10 current ARS-UI_Ramb_v3.0 (GCF_016772045.2) 2 NC_056055.1 (126892607..126926153)

Chromosome 2 - NC_056055.1Genomic Context describing neighboring genes Neighboring gene endogenous retrovirus group S71 member 1 Env polyprotein-like Neighboring gene uncharacterized LOC106990360 Neighboring gene U6 spliceosomal RNA Neighboring gene heat shock factor-binding protein 1

Genomic Sequence:
NC_056055.1 Chromosome 2 Reference ARS-UI_Ramb_v3.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Ovis aries Rambouillet Genome sequencing and assembly
  • BioProject: PRJNA414087
  • Analysis date: Thu Jan 09 10:41:41 2025

Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
secreted frizzled-related protein 3

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RefSeqs of Annotated Genomes: GCF_016772045.2-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ARS-UI_Ramb_v3.0 Primary Assembly

Genomic

  1. NC_056055.1 Reference ARS-UI_Ramb_v3.0 Primary Assembly

    Range
    126892607..126926153
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027964769.3 → XP_027820570.1  secreted frizzled-related protein 3

    UniProtKB/TrEMBL
    A0ACI6NYU1
    Related
    ENSOARP00285002268.1, ENSOART00285005556.1
    Conserved Domains (2) summary
    cd07441
    Location:32 → 157
    CRD_SFRP3; Cysteine-rich domain of the secreted frizzled-related protein 3 (SFRP3, alias FRZB), a Wnt antagonist
    cd03581
    Location:188 → 297
    NTR_Sfrp3_like; NTR domain, Secreted frizzled-related protein (Sfrp) 3-like subfamily; composed of proteins similar to human Sfrp3 and Sfrp4. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse functions ...
Nucleotide Protein Strain
Heading Accession and Version

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