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SMPD1 sphingomyelin phosphodiesterase 1 [ Felis catus (domestic cat) ]

Gene ID: 101099497, updated on 5-Aug-2026
Official Symbol
SMPD1
Official Full Name
sphingomyelin phosphodiesterase 1
Primary source
VGNC:VGNC:65501
See related
Ensembl:ENSFCTG00005018692
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
all
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See SMPD1 in Genome Data Viewer
Location:
chromosome: D1
Exon count:
6
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) D1 NC_058377.1 (63260124..63264778)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) D1 NC_018732.3 (65188287..65192945)

Chromosome D1 - NC_058377.1Genomic Context describing neighboring genes Neighboring gene TBC1 domain family member 12-like Neighboring gene caveolae associated protein 3 Neighboring gene amyloid beta precursor protein binding family B member 1 Neighboring gene uncharacterized LOC109491982 Neighboring gene hemopexin

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables acid sphingomyelin phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ceramide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sphingomyelin catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
sphingomyelin phosphodiesterase

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058377.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    63260124..63264778
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045038859.1 → XP_044894794.1  sphingomyelin phosphodiesterase isoform X2

    Conserved Domains (2) summary
    smart00741
    Location:77 → 150
    SapB; Saposin (B) Domains
    cd00842
    Location:191 → 483
    MPP_ASMase; acid sphingomyelinase and related proteins, metallophosphatase domain

  2. XM_006937046.4 → XP_006937108.1  sphingomyelin phosphodiesterase isoform X1

    UniProtKB/TrEMBL
    A0ABI7YXE1
    Related
    ENSFCTP00005039561.1, ENSFCTT00005053789.1
    Conserved Domains (2) summary
    smart00741
    Location:77 → 150
    SapB; Saposin (B) Domains
    cd00842
    Location:191 → 486
    MPP_ASMase; acid sphingomyelinase and related proteins, metallophosphatase domain
Nucleotide Protein
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