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TPO thyroid peroxidase [ Felis catus (domestic cat) ]

Gene ID: 101098706, updated on 8-Apr-2026
Official Symbol
TPO
Official Full Name
thyroid peroxidase
Primary source
VGNC:VGNC:66480
See related
Ensembl:ENSFCTG00005000158
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
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Try the new Transcripts and proteins table
See TPO in Genome Data Viewer
Location:
chromosome: A3
Exon count:
17
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) A3 NC_058370.1 (139559349..139607018, complement)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) A3 NC_018725.3 (142315776..142360654, complement)

Chromosome A3 - NC_058370.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC109498481 Neighboring gene peroxidasin Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC123384656 Neighboring gene mortality factor 4-like protein 1 Neighboring gene syntrophin gamma 2

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables heme binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables iodide peroxidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in response to oxidative stress IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in thyroid hormone generation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
thyroid peroxidase

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058370.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    139559349..139607018 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045055112.1XP_044911047.1  thyroid peroxidase

    UniProtKB/TrEMBL
    A0ABI7VPX8
    Related
    ENSFCTP00005000178.1, ENSFCTT00005000417.1
    Conserved Domains (2) summary
    cd09825
    Location:207774
    thyroid_peroxidase; Thyroid peroxidase (TPO)
    smart00179
    Location:836879
    EGF_CA; Calcium-binding EGF-like domain