U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MTM1 myotubularin 1 [ Felis catus (domestic cat) ]

Gene ID: 101093757, updated on 10-Feb-2026
Official Symbol
MTM1
Official Full Name
myotubularin 1
Primary source
VGNC:VGNC:68343
See related
Ensembl:ENSFCTG00005000523
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
Try the new Gene page
Try the new Transcripts and proteins table
See MTM1 in Genome Data Viewer
Location:
chromosome: X
Exon count:
17
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) X NC_058386.1 (122897910..122996163)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) X NC_018741.3 (125870997..125968998)

Chromosome X - NC_058386.1Genomic Context describing neighboring genes Neighboring gene endothelium and lymphocyte associated ASCH domain 2 Neighboring gene mastermind like domain containing 1 Neighboring gene U6 spliceosomal RNA Neighboring gene myotubularin related protein 1 Neighboring gene CD99 molecule like 2

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in dephosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in mitochondrion distribution IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in muscle cell cellular homeostasis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of autophagosome assembly IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
Preferred Names
myotubularin

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058386.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    122897910..122996163
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023249466.2XP_023105234.1  myotubularin isoform X1

    UniProtKB/TrEMBL
    A0ABI7VR90, A0ABI7VR93
    Related
    ENSFCTP00005000681.1, ENSFCTT00005001377.1
    Conserved Domains (2) summary
    cd13355
    Location:44143
    PH-GRAM_MTM1; Myotubularian 1 protein (MTM1) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam06602
    Location:166489
    Myotub-related; Myotubularin-like phosphatase domain
  2. XM_023249467.2XP_023105235.1  myotubularin isoform X2

    UniProtKB/TrEMBL
    A0ABI7VS50, A0ABI7VSP1
    Related
    ENSFCTP00005000675.1, ENSFCTT00005001371.1
    Conserved Domains (2) summary
    pfam06602
    Location:129452
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:44106
    PH-like; Pleckstrin homology-like domain
  3. XM_045050411.1XP_044906346.1  myotubularin isoform X5

    UniProtKB/TrEMBL
    A0ABI7VSP1
    Conserved Domains (2) summary
    cd14591
    Location:152400
    PTP-MTM1; protein tyrosine phosphatase-like domain of myotubularin phosphoinositide phosphatase 1
    cl17171
    Location:4477
    PH-like; Pleckstrin homology-like domain
  4. XM_023249468.2XP_023105236.1  myotubularin isoform X3

    UniProtKB/TrEMBL
    A0ABI7VR90, A0ABI7VSC3
    Related
    ENSFCTP00005000672.1, ENSFCTT00005001368.1
    Conserved Domains (2) summary
    pfam06602
    Location:119442
    Myotub-related; Myotubularin-like phosphatase domain
    cl17171
    Location:1596
    PH-like; Pleckstrin homology-like domain
  5. XM_004000974.5XP_004001023.1  myotubularin isoform X1

    UniProtKB/TrEMBL
    A0ABI7VR90, A0ABI7VR93
    Conserved Domains (2) summary
    cd13355
    Location:44143
    PH-GRAM_MTM1; Myotubularian 1 protein (MTM1) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    pfam06602
    Location:166489
    Myotub-related; Myotubularin-like phosphatase domain
  6. XM_045050410.1XP_044906345.1  myotubularin isoform X4

    UniProtKB/TrEMBL
    A0ABI7VR90
    Conserved Domains (2) summary
    cd14591
    Location:154402
    PTP-MTM1; protein tyrosine phosphatase-like domain of myotubularin phosphoinositide phosphatase 1
    cl17171
    Location:974
    PH-like; Pleckstrin homology-like domain