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ITGB2 integrin subunit beta 2 [ Felis catus (domestic cat) ]

Gene ID: 101087258, updated on 14-May-2025
Official Symbol
ITGB2
Official Full Name
integrin subunit beta 2
Primary source
VGNC:VGNC:67850
See related
Ensembl:ENSFCTG00005025355
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
human mouse all
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Location:
chromosome: C2
Exon count:
18
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) C2 NC_058376.1 (1755806..1781525)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) C2 NC_018731.3 (1762922..1788480)

Chromosome C2 - NC_058376.1Genomic Context describing neighboring genes Neighboring gene adenosine deaminase RNA specific B1 Neighboring gene SLX9 ribosome biogenesis factor Neighboring gene PTTG1 interacting protein Neighboring gene ubiquitin conjugating enzyme E2 G2 Neighboring gene small ubiquitin like modifier 3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Feline leukocyte adhesion (CD18) deficiency caused by a deletion in the integrin β(2) (ITGB2) gene. Bauer TR Jr, et al. Vet Clin Pathol, 2017 Sep. PMID 28750142, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables amyloid-beta binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
integrin beta-2

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058376.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    1755806..1781525
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011285804.4 → XP_011284106.2  integrin beta-2

    UniProtKB/TrEMBL
    A0A222NT34
    Related
    ENSFCTP00005051090.1, ENSFCTT00005072091.1
    Conserved Domains (1) summary
    smart00187
    Location:33 → 447
    INB; Integrin beta subunits (N-terminal portion of extracellular region)

  2. XM_045036502.1 → XP_044892437.1  integrin beta-2

    UniProtKB/TrEMBL
    A0A222NT34
    Related
    ENSFCTP00005051014.1, ENSFCTT00005071950.1
    Conserved Domains (1) summary
    smart00187
    Location:33 → 447
    INB; Integrin beta subunits (N-terminal portion of extracellular region)

  3. XM_045036503.1 → XP_044892438.1  integrin beta-2

    UniProtKB/TrEMBL
    A0A222NT34
    Conserved Domains (1) summary
    smart00187
    Location:33 → 447
    INB; Integrin beta subunits (N-terminal portion of extracellular region)
Nucleotide Protein
Heading Accession and Version

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Molecular Biology Databases
Research Materials