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CYBB cytochrome b-245 beta chain [ Felis catus (domestic cat) ]

Gene ID: 101086207, updated on 17-Aug-2024

Summary

Official Symbol
CYBB
Official Full Name
cytochrome b-245 beta chain
Primary source
VGNC:VGNC:61313
See related
EnsemblRapid:ENSFCTG00005001029
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
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Genomic context

See CYBB in Genome Data Viewer
Location:
chromosome: X
Exon count:
13
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) X NC_058386.1 (33186596..33220513)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) X NC_018741.3 (33385703..33419837)

Chromosome X - NC_058386.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC123383399 Neighboring gene LanC like family member 3 Neighboring gene histone H2A-Bbd type 1-like Neighboring gene X-linked Kx blood group antigen, Kell and VPS13A binding protein Neighboring gene uncharacterized LOC123383363 Neighboring gene dynein light chain Tctex-type 3

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables superoxide-generating NAD(P)H oxidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in defense response IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in superoxide anion generation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of NADPH oxidase complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
cytochrome b-245 heavy chain

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058386.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    33186596..33220513
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_004000394.5XP_004000443.1  cytochrome b-245 heavy chain

    UniProtKB/TrEMBL
    A0A5F5XGA9, M3VZS9
    Related
    ENSFCTP00005001569.1, ENSFCTT00005002676.1
    Conserved Domains (2) summary
    cd06186
    Location:297570
    NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
    pfam01794
    Location:65219
    Ferric_reduct; Ferric reductase like transmembrane component