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MFSD8 major facilitator superfamily domain containing 8 [ Felis catus (domestic cat) ]

Gene ID: 101084281, updated on 5-Aug-2026
Official Symbol
MFSD8
Official Full Name
major facilitator superfamily domain containing 8
Primary source
VGNC:VGNC:63485
See related
Ensembl:ENSFCTG00005011192
Gene type
protein coding
RefSeq status
MODEL
Organism
Felis catus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis
Orthologs
all
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Try the new Transcripts and proteins table
See MFSD8 in Genome Data Viewer
Location:
chromosome: B1
Exon count:
18
Annotation release Status Assembly Chr Location
105 current F.catus_Fca126_mat1.0 (GCF_018350175.1) B1 NC_058371.1 (96530858..96681414)
104 previous assembly Felis_catus_9.0 (GCF_000181335.3) B1 NC_018726.3 (98898000..98959444)

Chromosome B1 - NC_058371.1Genomic Context describing neighboring genes Neighboring gene progesterone receptor membrane component 2 Neighboring gene La ribonucleoprotein 1B Neighboring gene abhydrolase domain containing 18 Neighboring gene polo like kinase 4 Neighboring gene heat shock protein family A (Hsp70) member 4 like Neighboring gene solute carrier family 25 member 31

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A major facilitator superfamily domain 8 frameshift variant in a cat with suspected neuronal ceroid lipofuscinosis. Guevar J, et al. J Vet Intern Med, 2020 Jan. PMID 31860737, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A major facilitator superfamily domain 8 frameshift variant in a cat with suspected neuronal ceroid lipofuscinosis.
    Title: A major facilitator superfamily domain 8 frameshift variant in a cat with suspected neuronal ceroid lipofuscinosis.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
major facilitator superfamily domain-containing protein 8

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Felis catus Annotation Release 105 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference F.catus_Fca126_mat1.0 Primary Assembly

Genomic

  1. NC_058371.1 Reference F.catus_Fca126_mat1.0 Primary Assembly

    Range
    96530858..96681414
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045055884.1 → XP_044911819.1  major facilitator superfamily domain-containing protein 8 isoform X1

    UniProtKB/TrEMBL
    A0ABI7XED1, A0ABI7XFC3
    Related
    ENSFCTP00005020904.1, ENSFCTT00005031668.1
    Conserved Domains (1) summary
    cd17326
    Location:40 → 508
    MFS_MFSD8; Major facilitator superfamily domain-containing protein 8

  2. XM_019828987.3 → XP_019684546.2  major facilitator superfamily domain-containing protein 8 isoform X2

    UniProtKB/TrEMBL
    A0ABI7XEB3, A0ABI7XFC3
    Related
    ENSFCTP00005020847.1, ENSFCTT00005031605.1
    Conserved Domains (1) summary
    cd17326
    Location:40 → 463
    MFS_MFSD8; Major facilitator superfamily domain-containing protein 8

  3. XM_019828989.2 → XP_019684548.2  major facilitator superfamily domain-containing protein 8 isoform X4

    UniProtKB/TrEMBL
    A0ABI7XDM4, A0ABI7XH87
    Related
    ENSFCTP00005020650.1, ENSFCTT00005031381.1
    Conserved Domains (1) summary
    cd17326
    Location:40 → 441
    MFS_MFSD8; Major facilitator superfamily domain-containing protein 8

  4. XM_011281678.4 → XP_011279980.2  major facilitator superfamily domain-containing protein 8 isoform X3

    UniProtKB/TrEMBL
    A0ABI7XFC3
    Conserved Domains (1) summary
    cd17326
    Location:40 → 451
    MFS_MFSD8; Major facilitator superfamily domain-containing protein 8

  5. XM_019828986.3 → XP_019684545.2  major facilitator superfamily domain-containing protein 8 isoform X1

    UniProtKB/TrEMBL
    A0ABI7XED1, A0ABI7XFC3
    Conserved Domains (1) summary
    cd17326
    Location:40 → 508
    MFS_MFSD8; Major facilitator superfamily domain-containing protein 8

  6. XM_006930873.5 → XP_006930935.3  major facilitator superfamily domain-containing protein 8 isoform X1

    UniProtKB/TrEMBL
    A0ABI7XED1, A0ABI7XFC3
    Conserved Domains (1) summary
    cd17326
    Location:40 → 508
    MFS_MFSD8; Major facilitator superfamily domain-containing protein 8

RNA

  1. XR_006596767.1 RNA Sequence

  2. XR_006596768.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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