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TBC1D3K TBC1 domain family member 3K [ Homo sapiens (human) ]

Gene ID: 101060351, updated on 24-Nov-2020

Summary

Official Symbol
TBC1D3Kprovided by HGNC
Official Full Name
TBC1 domain family member 3Kprovided by HGNC
Primary source
HGNC:HGNC:51245
See related
Ensembl:ENSG00000273513
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in testis (RPKM 14.9), skin (RPKM 9.2) and 23 other tissues See more

Genomic context

See TBC1D3K in Genome Data Viewer
Location:
17q12
Exon count:
14
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (37923805..37935371)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 7 Neighboring gene RNA, U6 small nuclear 489, pseudogene Neighboring gene uncharacterized LOC102723608 Neighboring gene nitric oxide synthase 2, inducible pseudogene

Genomic regions, transcripts, and products

Genomic Sequence:
NC_000017.11 Chromosome 17 Reference GRCh38.p13 Primary Assembly

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
small GTPase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
activation of GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
TBC1 domain family member 3K
Names
TBC1 domain family member-like

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291464.1NP_001278393.1  TBC1 domain family member 3K

    See identical proteins and their annotated locations for NP_001278393.1

    Status: VALIDATED

    Source sequence(s)
    AC243569
    Consensus CDS
    CCDS74042.1
    UniProtKB/Swiss-Prot
    A0A087X1G2
    Related
    ENSP00000484181.1, ENST00000620247.1
    Conserved Domains (1) summary
    smart00164
    Location:99312
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    37923805..37935371
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006722235.2XP_006722298.1  TBC1 domain family member 3K isoform X1

    See identical proteins and their annotated locations for XP_006722298.1

    Conserved Domains (1) summary
    smart00164
    Location:160373
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
  2. XM_011524173.1XP_011522475.1  TBC1 domain family member 3K isoform X3

    Conserved Domains (1) summary
    smart00164
    Location:160372
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
  3. XM_011524172.1XP_011522474.1  TBC1 domain family member 3K isoform X2

    Conserved Domains (1) summary
    smart00164
    Location:160351
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
  4. XM_006722237.2XP_006722300.1  TBC1 domain family member 3K isoform X4

    See identical proteins and their annotated locations for XP_006722300.1

    UniProtKB/Swiss-Prot
    A0A087X1G2
    Conserved Domains (1) summary
    smart00164
    Location:99312
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
  5. XM_006722239.2XP_006722302.1  TBC1 domain family member 3K isoform X5

    Conserved Domains (1) summary
    smart00164
    Location:99290
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
  6. XM_006722236.1XP_006722299.1  TBC1 domain family member 3K isoform X1

    See identical proteins and their annotated locations for XP_006722299.1

    Conserved Domains (1) summary
    smart00164
    Location:160373
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
  7. XM_011524174.1XP_011522476.1  TBC1 domain family member 3K isoform X6

    Conserved Domains (1) summary
    smart00164
    Location:160361
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
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