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OPN1MW3 opsin 1, medium wave sensitive 3 [ Homo sapiens (human) ]

Gene ID: 101060233, updated on 13-May-2022

Summary

Official Symbol
OPN1MW3provided by HGNC
Official Full Name
opsin 1, medium wave sensitive 3provided by HGNC
Primary source
HGNC:HGNC:51831
See related
Ensembl:ENSG00000269433 AllianceGenome:HGNC:51831
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GCP; GOP; OPN1MW; OPN1MW2
Summary
Enables identical protein binding activity and photoreceptor activity. Involved in positive regulation of cytokinesis. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See OPN1MW3 in Genome Data Viewer
Location:
Xq28
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (154257582..154271090)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X (PATCHES) NW_003871103.3 (1691561..1705069)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene opsin 1, medium wave sensitive 2 Neighboring gene TEX28 pseudogene 3 Neighboring gene testis expressed 28 Neighboring gene transketolase like 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled photoreceptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cellular response to light stimulus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in detection of visible light IEA
Inferred from Electronic Annotation
more info
 
involved_in phototransduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in protein-chromophore linkage IEA
Inferred from Electronic Annotation
more info
 
involved_in visual perception IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in photoreceptor outer segment IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
medium-wave-sensitive opsin 3
Names
Medium-wave-sensitive opsin 2
Opsin 1 cone pigments medium-wave-sensitive 2
green cone photoreceptor pigment
green-sensitive opsin
opsin 1 (cone pigments), medium-wave-sensitive 3
opsin 1 cone pigments medium-wave-sensitive 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001330067.2NP_001316996.1  medium-wave-sensitive opsin 3

    Status: VALIDATED

    Source sequence(s)
    AC245140
    Consensus CDS
    CCDS83509.1
    UniProtKB/Swiss-Prot
    P04001, P0DN77, P0DN78
    Related
    ENSP00000469970.1, ENST00000599405.3
    Conserved Domains (2) summary
    pfam00001
    Location:71322
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:61178
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    154257582..154271090
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)