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FMC1-LUC7L2 FMC1-LUC7L2 readthrough [ Homo sapiens (human) ]

Gene ID: 100996928, updated on 3-Sep-2021

Summary

Official Symbol
FMC1-LUC7L2provided by HGNC
Official Full Name
FMC1-LUC7L2 readthroughprovided by HGNC
Primary source
HGNC:HGNC:44671
See related
Ensembl:ENSG00000269955
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FMC1; C7orf55; C7orf55-LUC7L2
Summary
This locus represents naturally occurring readthrough transcription between the neighboring C7orf55 (chromosome 7 open reading frame 55) and LUC7L2 (LUC7-like 2) genes on chromosome 7. The readthrough transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Jul 2012]
Expression
Ubiquitous expression in thyroid (RPKM 38.8), bone marrow (RPKM 34.2) and 25 other tissues See more
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Genomic context

See FMC1-LUC7L2 in Genome Data Viewer
Location:
7q34
Exon count:
11
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 7 NC_000007.14 (139341337..139423454)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (139026083..139108200)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene ubinuclein 2 Neighboring gene RNA, U6 small nuclear 206, pseudogene Neighboring gene tRNA-Arg (anticodon CCT) 4-1 Neighboring gene LUC7 like 2, pre-mRNA splicing factor Neighboring gene formation of mitochondrial complex V assembly factor 1 homolog Neighboring gene uncharacterized LOC100129148 Neighboring gene killer cell lectin like receptor G2 Neighboring gene RNA, U6 small nuclear 911, pseudogene Neighboring gene ST13, Hsp70 interacting protein pseudogene 17

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
FMC1-LUC7L2 readthrough protein
Names
ATP synthase assembly factor FMC1, mitochondrial
C7orf55-LUC7L2 readthrough
Formation of mitochondrial complex V assembly factor 1 homolog
Protein FMC1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001244584.3NP_001231513.1  FMC1-LUC7L2 readthrough protein

    See identical proteins and their annotated locations for NP_001231513.1

    Status: VALIDATED

    Source sequence(s)
    AC083880, AC083883, AK297642
    Consensus CDS
    CCDS59084.1
    UniProtKB/Swiss-Prot
    Q96HJ9
    UniProtKB/TrEMBL
    A0A0A6YYJ8
    Related
    ENSP00000440222.1, ENST00000541515.3
    Conserved Domains (3) summary
    COG5200
    Location:89294
    LUC7; U1 snRNP component, mediates U1 snRNP association with cap-binding complex [RNA processing and modification]
    pfam03194
    Location:91307
    LUC7; LUC7 N_terminus
    pfam13233
    Location:9101
    Complex1_LYR_2; Complex1_LYR-like

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p13 Primary Assembly

    Range
    139341337..139423454
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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