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MX1 MX dynamin like GTPase 1 [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100988065, updated on 3-Apr-2024

Summary

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Gene symbol
MX1
Gene description
MX dynamin like GTPase 1
See related
Ensembl:ENSPPAG00000034486
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Also known as
MxA
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 22
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 22 NC_073271.2 (37503227..37541972)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 21 NC_073270.1 (32357510..32396253)

Chromosome 22 - NC_073271.2Genomic Context describing neighboring genes Neighboring gene MX dynamin like GTPase 2 Neighboring gene uncharacterized LOC134729727 Neighboring gene transmembrane serine protease 2 Neighboring gene small nucleolar RNA SNORA32

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evolution-guided identification of antiviral specificity determinants in the broadly acting interferon-induced innate immunity factor MxA. Mitchell PS, et al. Cell Host Microbe, 2012 Oct 18. PMID 23084925, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in microtubule IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interferon-induced GTP-binding protein Mx1
Names
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001301762.1 → NP_001288691.1  interferon-induced GTP-binding protein Mx1

    See identical proteins and their annotated locations for NP_001288691.1

    Status: PROVISIONAL

    Source sequence(s)
    JX297241
    UniProtKB/TrEMBL
    A0A2R9B3I9, K4JEZ2
    Related
    ENSPPAP00000022695.1, ENSPPAT00000045507.1
    Conserved Domains (3) summary
    smart00302
    Location:573 → 660
    GED; Dynamin GTPase effector domain
    cd08771
    Location:68 → 340
    DLP_1; Dynamin_like protein family includes dynamins and Mx proteins
    pfam01031
    Location:260 → 546
    Dynamin_M; Dynamin central region

RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073271.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    37503227..37541972
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_055105129.2 → XP_054961104.2  interferon-induced GTP-binding protein Mx1 isoform X1

    UniProtKB/TrEMBL
    K4JEZ2

  2. XM_034947818.3 → XP_034803709.3  interferon-induced GTP-binding protein Mx1 isoform X1

    UniProtKB/TrEMBL
    K4JEZ2

  3. XM_055105128.2 → XP_054961103.2  interferon-induced GTP-binding protein Mx1 isoform X1

    UniProtKB/TrEMBL
    K4JEZ2

  4. XM_063601250.1 → XP_063457320.1  interferon-induced GTP-binding protein Mx1 isoform X1

    UniProtKB/TrEMBL
    K4JEZ2

  5. XM_055105125.2 → XP_054961100.2  interferon-induced GTP-binding protein Mx1 isoform X1

    UniProtKB/TrEMBL
    K4JEZ2

  6. XM_003823901.7 → XP_003823949.4  interferon-induced GTP-binding protein Mx1 isoform X1

    UniProtKB/TrEMBL
    K4JEZ2

  7. XM_055105127.2 → XP_054961102.2  interferon-induced GTP-binding protein Mx1 isoform X1

    UniProtKB/TrEMBL
    K4JEZ2

  8. XM_008977599.4 → XP_008975847.4  interferon-induced GTP-binding protein Mx1 isoform X1

    UniProtKB/TrEMBL
    K4JEZ2

  9. XM_055105124.2 → XP_054961099.2  interferon-induced GTP-binding protein Mx1 isoform X1

    UniProtKB/TrEMBL
    K4JEZ2

  10. XM_008977603.4 → XP_008975851.4  interferon-induced GTP-binding protein Mx1 isoform X1

    UniProtKB/TrEMBL
    K4JEZ2

  11. XM_055105126.2 → XP_054961101.2  interferon-induced GTP-binding protein Mx1 isoform X1

    UniProtKB/TrEMBL
    K4JEZ2

  12. XM_008977598.6 → XP_008975846.4  interferon-induced GTP-binding protein Mx1 isoform X1

    UniProtKB/TrEMBL
    K4JEZ2

  13. XM_063601251.1 → XP_063457321.1  interferon-induced GTP-binding protein Mx1 isoform X1

    UniProtKB/TrEMBL
    K4JEZ2

  14. XM_034947821.3 → XP_034803712.3  interferon-induced GTP-binding protein Mx1 isoform X2

Nucleotide Protein
Heading Accession and Version

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