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RANGRF RAN guanine nucleotide release factor [ Pan paniscus (pygmy chimpanzee) ]

Gene ID: 100976590, updated on 8-Mar-2024

Summary

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Gene symbol
RANGRF
Gene description
RAN guanine nucleotide release factor
See related
Ensembl:ENSPPAG00000021562
Gene type
protein coding
RefSeq status
MODEL
Organism
Pan paniscus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current NHGRI_mPanPan1-v2.0_pri (GCF_029289425.2) 19 NC_073268.2 (65464267..65465922, complement)
RS_2023_05 previous assembly NHGRI_mPanPan1-v1.1-0.1.freeze_pri (GCF_029289425.1) 17 NC_073266.1 (70273759..70275232, complement)

Chromosome 19 - NC_073268.2Genomic Context describing neighboring genes Neighboring gene Rho guanine nucleotide exchange factor 15 Neighboring gene uncharacterized LOC117976550 Neighboring gene small ribosomal subunit protein eS24-like Neighboring gene solute carrier family 25 member 35 Neighboring gene uncharacterized LOC134729456 Neighboring gene phosphoribosylformylglycinamidine synthase Neighboring gene CST telomere replication complex component 1 Neighboring gene transfer RNA isoleucine (anticodon AAU)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables small GTPase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sodium channel regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane transporter binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in heart contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein import into nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of membrane depolarization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of sodium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ran guanine nucleotide release factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_029289425.2-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

Genomic

  1. NC_073268.2 Reference NHGRI_mPanPan1-v2.0_pri Primary Assembly

    Range
    65464267..65465922 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003818066.6 → XP_003818114.2  ran guanine nucleotide release factor

    UniProtKB/TrEMBL
    A0A2R8ZQT8
    Conserved Domains (1) summary
    cd00224
    Location:7 → 184
    Mog1; homolog to Ran-Binding Protein Mog1p; binds to the small GTPase Ran, which plays an important role in nuclear import. Binding is independent of Ran's nucleotide state (RanGTP/RanGDP)
Nucleotide Protein
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