Clec3b C-type lectin domain family 3, member B [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Clec3bprovided by RGD
Official Full Name: C-type lectin domain family 3, member Bprovided by RGD
Primary source: RGD:1311031
See related: AllianceGenome:RGD:1311031
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Tna
Summary: Predicted to enable calcium ion binding activity; heparin binding activity; and kringle domain binding activity. Involved in ossification. Predicted to be located in cytoplasm and granular component. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in osteoarthritis and retinal macular dystrophy 4. Orthologous to human CLEC3B (C-type lectin domain family 3 member B). [provided by Alliance of Genome Resources, Jul 2025]
Expression: Biased expression in Lung (RPKM 73.7), Muscle (RPKM 50.2) and 8 other tissues See more
Orthologs: all
: Try the new Gene page
Try the new Transcripts and proteins table

Genomic context

Location:: 8q32

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	8	NC_086026.1 (131687575..131693292)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	8	NC_051343.1 (122810120..122815837)

Chromosome 8 - NC_086026.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

age-related changes in preadipocyte gene expression differ among depots, potentially contributing to fat redistribution and dysfunction.
Title: Aging, depot origin, and preadipocyte gene expression.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

AU049759 (e-PCR)
- UniSTS:146205

D8Rat71 (e-PCR), detects polymorphism
- UniSTS:119130

RH143893 (e-PCR)
- UniSTS:233139

Clec3b (e-PCR), detects polymorphism
- UniSTS:519415

General protein information

Go to the top of the page Help

Preferred Names: tetranectin

Names: tetranectin (plasminogen binding protein); tetranectin-like

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001398638.1 → NP_001385567.1 tetranectin precursor

Status: VALIDATED

Source sequence(s)

JAXUCZ010000008

Conserved Domains (1) summary

cd03596
Location:71 → 199

CLECT_tetranectin_like; C-type lectin-like domain (CTLD) of the type found in the tetranectin (TN), cartilage derived C-type lectin (CLECSF1), and stem cell growth factor (SCGF)