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KIT KIT proto-oncogene, receptor tyrosine kinase [ Capra hircus (goat) ]

Gene ID: 100861386, updated on 5-Aug-2026
Gene symbol
KIT
Gene description
KIT proto-oncogene, receptor tyrosine kinase
See related
Ensembl:ENSCHIG00000022287
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Capra hircus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Caprinae; Capra
Also known as
SCFR
Orthologs
all
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See KIT in Genome Data Viewer
Location:
chromosome: 6
Exon count:
21
Annotation release Status Assembly Chr Location
102 current ASM170441v1 (GCF_001704415.1) 6 NC_030813.1 (70711232..70793908)
101 previous assembly CHIR_1.0 (GCF_000317765.1) 6 NC_022298.1 (68316048..68361679)

Chromosome 6 - NC_030813.1Genomic Context describing neighboring genes Neighboring gene platelet derived growth factor receptor alpha Neighboring gene mitochondrial pyruvate carrier 2 pseudogene Neighboring gene 60S ribosomal protein L17 pseudogene Neighboring gene uncharacterized LOC108636277

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Antibody preparation and identification of the Cashmere goat c-kit protein in the testes. Wu SC, et al. Genet Mol Res, 2014 Jul 2. PMID 25062419
  2. Molecular cloning of cDNA encoding the c-kit receptor of Shiba goats and a novel alanine insertion specific to goats and sheep in the kinase insert region. Tanaka S, et al. Biochim Biophys Acta, 1997 May 30. PMID 9199245
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. c-kit is primarily expressed in the spermatogonia and spermatocytes of goat testes.
    Title: Antibody preparation and identification of the Cashmere goat c-kit protein in the testes.
Submit: New GeneRIF Correction

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in B cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in Fc receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in Kit signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MAP kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of signaling receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
mast/stem cell growth factor receptor Kit
Names
Proto-oncogene c-Kit
Tyrosine-protein kinase Kit
c-kit receptor
caprine c-kit protein
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncoprotein
NP_001272653.1
XP_017904645.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001285724.1 → NP_001272653.1  mast/stem cell growth factor receptor Kit precursor

    See identical proteins and their annotated locations for NP_001272653.1

    Status: PROVISIONAL

    Source sequence(s)
    D45168
    UniProtKB/Swiss-Prot
    Q28317
    UniProtKB/TrEMBL
    J7GNJ8
    Related
    ENSCHIP00000025801.1, ENSCHIT00000033663.1
    Conserved Domains (7) summary
    cd00096
    Location:427 → 506
    Ig; Immunoglobulin domain
    cd05860
    Location:312 → 412
    Ig4_SCFR; Fourth immunoglobulin (Ig)-like domain of stem cell factor receptor (SCFR)
    smart00409
    Location:427 → 506
    IG; Immunoglobulin
    smart00410
    Location:220 → 308
    IG_like; Immunoglobulin like
    cd05104
    Location:554 → 930
    PTKc_Kit; Catalytic domain of the Protein Tyrosine Kinase, Kit
    pfam00047
    Location:216 → 306
    ig; Immunoglobulin domain
    pfam07714
    Location:590 → 926
    Pkinase_Tyr; Protein tyrosine kinase

RefSeqs of Annotated Genomes: Capra hircus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM170441v1 Primary Assembly

Genomic

  1. NC_030813.1 Reference ASM170441v1 Primary Assembly

    Range
    70711232..70793908
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018049156.1 → XP_017904645.1  mast/stem cell growth factor receptor Kit isoform X1

    UniProtKB/TrEMBL
    A0A452FN97, J7GNJ8
    Related
    ENSCHIP00000025751.1, ENSCHIT00000033613.1
    Conserved Domains (5) summary
    cd05104
    Location:550 → 926
    PTKc_Kit; Catalytic domain of the Protein Tyrosine Kinase, Kit
    pfam00047
    Location:216 → 306
    ig; Immunoglobulin domain
    pfam13927
    Location:413 → 496
    Ig_3; Immunoglobulin domain
    cd00096
    Location:229 → 233
    Ig; Ig strand B [structural motif]
    cd05860
    Location:312 → 412
    IgI_4_SCFR; Fourth immunoglobulin (Ig)-like domain of stem cell factor receptor (SCFR); member of the I-set of IgSF domains
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q28317.1 GenPept UniProtKB/Swiss-Prot:Q28317

Gene LinkOut

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Molecular Biology Databases
Research Materials