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HHLA1 HERV-H LTR-associating 1 [ Homo sapiens (human) ]

Gene ID: 10086, updated on 13-May-2022

Summary

Official Symbol
HHLA1provided by HGNC
Official Full Name
HERV-H LTR-associating 1provided by HGNC
Primary source
HGNC:HGNC:4904
See related
Ensembl:ENSG00000132297 MIM:604109; AllianceGenome:HGNC:4904
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PLA2L
Summary
Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See HHLA1 in Genome Data Viewer
Location:
8q24.22
Exon count:
17
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (132061480..132111157, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (133184384..133234063, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (133073727..133123404, complement)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene EFR3 homolog A Neighboring gene Sharpr-MPRA regulatory region 9765 Neighboring gene otoconin 90 Neighboring gene Sharpr-MPRA regulatory region 9796 Neighboring gene potassium voltage-gated channel subfamily Q member 3 Neighboring gene VISTA enhancer hs2563 Neighboring gene uncharacterized LOC105375765

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
HERV-H LTR-associating protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145095.3NP_001138567.1  HERV-H LTR-associating protein 1 precursor

    See identical proteins and their annotated locations for NP_001138567.1

    Status: VALIDATED

    Source sequence(s)
    AC100868, AC131042
    UniProtKB/Swiss-Prot
    C9JL84
    Related
    ENSP00000388322.1, ENST00000414222.2
    Conserved Domains (1) summary
    PHA03247
    Location:218443
    PHA03247; large tegument protein UL36; Provisional

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    132061480..132111157 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    133184384..133234063 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_005712.1: Suppressed sequence

    Description
    NM_005712.1: This RefSeq was permanently suppressed because it was based on a sequence that is found only in tumorigenic tissues and cells.