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PREB prolactin regulatory element binding [ Gallus gallus (chicken) ]

Gene ID: 100858986, updated on 17-Aug-2024

Summary

Official Symbol
PREBprovided by CGNC
Official Full Name
prolactin regulatory element bindingprovided by CGNC
Primary source
CGNC:64133
See related
Ensembl:ENSGALG00010009186
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
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Genomic context

See PREB in Genome Data Viewer
Location:
chromosome: 3
Exon count:
9
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (104320043..104322151, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (104080599..104082704, complement)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene cell growth regulator with EF-hand domain 1 Neighboring gene abhydrolase domain containing 1 Neighboring gene solute carrier family 5 member 6 Neighboring gene all-trans retinoic acid induced differentiation factor Neighboring gene U1 spliceosomal RNA

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein secretion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of COPII vesicle coating IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
guanine nucleotide-exchange factor SEC12; prolactin regulatory element-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001319023.2NP_001305952.2  guanine nucleotide-exchange factor SEC12

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000070
    UniProtKB/TrEMBL
    A0A077KY10
    Related
    ENSGALP00010012557.1, ENSGALT00010021933.1
    Conserved Domains (2) summary
    sd00039
    Location:154188
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:152317
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    104320043..104322151 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015285028.4XP_015140514.1  prolactin regulatory element-binding protein isoform X1

    UniProtKB/TrEMBL
    A0A077KY10
    Conserved Domains (3) summary
    COG2319
    Location:156363
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:154188
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:152329
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    104080599..104082704 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)