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Setdb2 SET domain bifurcated histone lysine methyltransferase 2 [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100774155, updated on 14-Nov-2024
Gene symbol
Setdb2
Gene description
SET domain bifurcated histone lysine methyltransferase 2
See related
Ensembl:ENSCGRG00015012318 Ensembl:ENSCGRG00015012440
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
all
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Try the new Transcripts and proteins table
See Setdb2 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
26
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003616652.1 (37491..104624)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276807.1 (214340420..214406870, complement)

NW_003616652.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103164501

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone H3K9 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in heterochromatin organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
histone-lysine N-methyltransferase SETDB2
Names
PHD finger protein 11
SET domain bifurcated 2

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003616652.1 Reference CriGri_1.0 Primary Assembly

    Range
    37491..104624
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007654601.4 → XP_007652791.2  histone-lysine N-methyltransferase SETDB2 isoform X3

    UniProtKB/TrEMBL
    A0A9J7HA57
    Conserved Domains (3) summary
    cd01395
    Location:150 → 210
    HMT_MBD; Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated ...
    cl40432
    Location:208 → 690
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
    cl22851
    Location:698 → 812
    PHD_SF; PHD finger superfamily

  2. XM_007654602.4 → XP_007652792.1  histone-lysine N-methyltransferase SETDB2 isoform X1

    See identical proteins and their annotated locations for XP_007652792.1

    UniProtKB/TrEMBL
    A0A8C2QFS4
    Conserved Domains (2) summary
    cd01395
    Location:150 → 210
    HMT_MBD; Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated ...
    cl40432
    Location:208 → 694
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily

  3. XM_016963546.2 → XP_016819035.1  histone-lysine N-methyltransferase SETDB2 isoform X1

    UniProtKB/TrEMBL
    A0A8C2QFS4
    Conserved Domains (2) summary
    cd01395
    Location:150 → 210
    HMT_MBD; Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated ...
    cl40432
    Location:208 → 694
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily

  4. XM_035437858.1 → XP_035293749.1  histone-lysine N-methyltransferase SETDB2 isoform X1

    UniProtKB/TrEMBL
    A0A8C2QFS4
    Conserved Domains (2) summary
    cd01395
    Location:150 → 210
    HMT_MBD; Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated ...
    cl40432
    Location:208 → 694
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily

  5. XM_003514485.5 → XP_003514533.1  histone-lysine N-methyltransferase SETDB2 isoform X1

    See identical proteins and their annotated locations for XP_003514533.1

    UniProtKB/TrEMBL
    A0A8C2QFS4
    Conserved Domains (2) summary
    cd01395
    Location:150 → 210
    HMT_MBD; Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated ...
    cl40432
    Location:208 → 694
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily

  6. XM_007654603.4 → XP_007652793.1  histone-lysine N-methyltransferase SETDB2 isoform X2

    See identical proteins and their annotated locations for XP_007652793.1

    UniProtKB/TrEMBL
    G3IIP3
    Conserved Domains (1) summary
    cl22851
    Location:28 → 142
    PHD_SF; PHD finger superfamily

Alternate CriGri-PICRH-1.0

Genomic

  1. NW_023276807.1 Alternate CriGri-PICRH-1.0

    Range
    214340420..214406870 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035452222.1 → XP_035308113.1  histone-lysine N-methyltransferase SETDB2 isoform X2

    UniProtKB/TrEMBL
    G3IIP3
    Related
    ENSCGRP00015053879.1, ENSCGRT00015056568.1
    Conserved Domains (1) summary
    cl22851
    Location:28 → 142
    PHD_SF; PHD finger superfamily

  2. XM_035452223.1 → XP_035308114.1  histone-lysine N-methyltransferase SETDB2 isoform X3

    UniProtKB/TrEMBL
    A0A9J7HA57
    Conserved Domains (3) summary
    cd01395
    Location:150 → 210
    HMT_MBD; Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated ...
    cl40432
    Location:208 → 690
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
    cl22851
    Location:698 → 812
    PHD_SF; PHD finger superfamily

  3. XM_027390427.2 → XP_027246228.1  histone-lysine N-methyltransferase SETDB2 isoform X1

    UniProtKB/TrEMBL
    A0A8C2QFS4
    Conserved Domains (2) summary
    cd01395
    Location:150 → 210
    HMT_MBD; Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated ...
    cl40432
    Location:208 → 694
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily

  4. XM_027390428.2 → XP_027246229.1  histone-lysine N-methyltransferase SETDB2 isoform X1

    UniProtKB/TrEMBL
    A0A8C2QFS4
    Conserved Domains (2) summary
    cd01395
    Location:150 → 210
    HMT_MBD; Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated ...
    cl40432
    Location:208 → 694
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily

  5. XM_027390425.2 → XP_027246226.1  histone-lysine N-methyltransferase SETDB2 isoform X1

    UniProtKB/TrEMBL
    A0A8C2QFS4
    Conserved Domains (2) summary
    cd01395
    Location:150 → 210
    HMT_MBD; Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated ...
    cl40432
    Location:208 → 694
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily

  6. XM_035452221.1 → XP_035308112.1  histone-lysine N-methyltransferase SETDB2 isoform X1

    UniProtKB/TrEMBL
    A0A8C2QFS4
    Related
    ENSCGRP00015016094.1, ENSCGRT00015019763.2
    Conserved Domains (2) summary
    cd01395
    Location:150 → 210
    HMT_MBD; Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated ...
    cl40432
    Location:208 → 694
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily

  7. XM_027390429.2 → XP_027246230.1  histone-lysine N-methyltransferase SETDB2 isoform X1

    UniProtKB/TrEMBL
    A0A8C2QFS4
    Conserved Domains (2) summary
    cd01395
    Location:150 → 210
    HMT_MBD; Methyl-CpG binding domains (MBD) present in putative histone methyltransferases (HMT) such as CLLD8 and SETDB1 proteins; CLLD8 contains a MBD, a PreSET and a bifurcated SET domain, suggesting that CLLD8 might be associated with methylation-mediated ...
    cl40432
    Location:208 → 694
    SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain superfamily
Nucleotide Protein Strain
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