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Dot1l DOT1 like histone lysine methyltransferase [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100771005, updated on 8-Mar-2024
Gene symbol
Dot1l
Gene description
DOT1 like histone lysine methyltransferase
Locus tag
I79_009265
See related
Ensembl:ENSCGRG00015002912
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
all
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See Dot1l in Genome Data Viewer
Location:
chromosome: 5
Exon count:
30
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613904.1 (1522542..1558166)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 5 NC_048598.1 (101534589..101578335)

NW_003613904.1Genomic Context describing neighboring genes Neighboring gene IZUMO family member 4 Neighboring gene adaptor related protein complex 3 subunit delta 1 Neighboring gene pleckstrin homology domain containing J1 Neighboring gene splicing factor 3a subunit 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone H3K79 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in heterochromatin formation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription regulatory region DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
histone-lysine N-methyltransferase, H3 lysine-79 specific
Names
DOT1-like histone H3K79 methyltransferase
Histone-lysine N-methyltransferase, H3 lysine-79 specific

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613904.1 Reference CriGri_1.0 Primary Assembly

    Range
    1522542..1558166
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016975683.2 → XP_016831172.2  histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1

    UniProtKB/TrEMBL
    G3HFA9
    Conserved Domains (5) summary
    pfam08123
    Location:116 → 318
    DOT1; Histone methylation protein DOT1
    PHA03247
    Location:998 → 1319
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:739 → 1126
    PHA03307; transcriptional regulator ICP4; Provisional
    TIGR04523
    Location:511 → 660
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    cd20902
    Location:482 → 546
    CC_DOT1L; coiled coil domain of disruptor of telomeric-silencing 1-like (DOT1L) and similar proteins

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048598.1 Alternate CriGri-PICRH-1.0

    Range
    101534589..101578335
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027419305.2 → XP_027275106.1  histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X2

    UniProtKB/TrEMBL
    A0A9J7G3B3, G3HFA9
    Related
    ENSCGRP00015003644.2, ENSCGRT00015004513.2

  2. XM_027419306.2 → XP_027275107.1  histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X2

    UniProtKB/TrEMBL
    A0A9J7G3B3, G3HFA9

  3. XM_027419307.2 → XP_027275108.1  histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X3

    UniProtKB/TrEMBL
    A0A9J7JQC9, G3HFA9

  4. XM_027419308.2 → XP_027275109.1  histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X4

    UniProtKB/TrEMBL
    A0A8C2N1P1, G3HFA9
Nucleotide Protein Strain
Heading Accession and Version

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