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Kmt2c lysine methyltransferase 2C [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100767367, updated on 5-Sep-2025
Gene symbol
Kmt2c
Gene description
lysine methyltransferase 2C
Locus tag
I79_007670
See related
Ensembl:ENSCGRG00015005764
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Also known as
Mll3
Annotation information
Annotation category: partial on reference assembly
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See Kmt2c in Genome Data Viewer
Location:
chromosome: 8
Exon count:
60
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613842.1 (75580..230671)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 8 NC_048601.1 (97048604..97242564)

NW_003613842.1Genomic Context describing neighboring genes Neighboring gene U1 spliceosomal RNA Neighboring gene chaperonin containing TCP1 subunit 8 like 2 Neighboring gene uncharacterized LOC118239868 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 11 Neighboring gene polypeptide N-acetylgalactosaminyltransferase like 5

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables histone H3K4 methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of MLL3/4 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
histone-lysine N-methyltransferase 2C
Names
Histone-lysine N-methyltransferase MLL3
lysine (K)-specific methyltransferase 2C
myeloid/lymphoid or mixed-lineage leukemia 3
XP_027284324.1

Length

  • 4991
XP_035311015.1

Length

  • 4916

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613842.1 Reference CriGri_1.0 Primary Assembly

    Range
    75580..230671
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035455124.1 → XP_035311015.1  histone-lysine N-methyltransferase 2C isoform X1

    UniProtKB/TrEMBL
    A0A8C2LFI8
    Conserved Domains (15) summary
    smart00398
    Location:1588 → 1641
    HMG; high mobility group
    PHA03247
    Location:1850 → 2294
    PHA03247; large tegument protein UL36; Provisional
    sd00025
    Location:1009 → 1031
    zf-RanBP2; RanBP2-type Zn finger [structural motif]
    cd15509
    Location:275 → 320
    PHD1_KMT2C_like; PHD finger 1 found in Histone-lysine N-methyltransferase 2C (KMT2C) and 2D (KMT2D)
    cd15511
    Location:398 → 449
    PHD3_KMT2C; PHD finger 3 found in Histone-lysine N-methyltransferase 2C (KMT2C)
    cd15513
    Location:934 → 980
    PHD5_KMT2C_like; PHD finger 5 found in Histone-lysine N-methyltransferase 2C (KMT2C) and PHD finger 4 found in KMT2D
    cd15594
    Location:322 → 367
    PHD2_KMT2C; PHD finger 2 found in Histone-lysine N-methyltransferase 2C (KMT2C)
    cd15600
    Location:1011 → 1061
    PHD6_KMT2C; PHD finger 6 found in Histone-lysine N-methyltransferase 2C (KMT2C)
    cd15696
    Location:179 → 262
    ePHD1_KMT2C; Extended PHD finger 1 found in histone-lysine N-methyltransferase 2C (KMT2C)
    cd15697
    Location:4407 → 4511
    ePHD2_KMT2C; Extended PHD finger 2 found in histone-lysine N-methyltransferase 2C (KMT2C)
    cd19171
    Location:4763 → 4915
    SET_KMT2C_2D; SET domain (including post-SET domain) found in histone-lysine N-methyltransferase 2C (KMT2C), 2D (KMT2D) and similar proteins
    pfam05964
    Location:4556 → 4607
    FYRN; F/Y-rich N-terminus
    pfam05965
    Location:4613 → 4697
    FYRC; F/Y rich C-terminus
    pfam13868
    Location:3132 → 3219
    TPH; Trichohyalin-plectin-homology domain
    cl22851
    Location:877 → 933
    PHD_SF; PHD finger superfamily

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048601.1 Alternate CriGri-PICRH-1.0

    Range
    97048604..97242564
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027428523.1 → XP_027284324.1  histone-lysine N-methyltransferase 2C isoform X2

    UniProtKB/TrEMBL
    A0A8C2LFI8, A0A9J7JWM7
    Related
    ENSCGRP00015058693.1, ENSCGRT00015070537.1
Nucleotide Protein Strain
Heading Accession and Version

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