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Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100758991, updated on 8-Mar-2024

Summary

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Gene symbol
Paics
Gene description
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
Locus tag
I79_022535
See related
Ensembl:ENSCGRG00015008011
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human all
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Genomic context

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See Paics in Genome Data Viewer
Location:
chromosome: 1
Exon count:
10
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003615992.1 (47612..61610)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276807.1 (143371545..143385543)

NW_003615992.1Genomic Context describing neighboring genes Neighboring gene aminoadipate-semialdehyde dehydrogenase Neighboring gene phosphoribosyl pyrophosphate amidotransferase Neighboring gene uncharacterized LOC103163085 Neighboring gene signal recognition particle 72 Neighboring gene ARF like GTPase 9

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: cellular models of de novo purine biosynthesis deficiency disorders. Duval N, et al. Mol Genet Metab, 2013 Mar. PMID 23394948, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphoribosylaminoimidazolesuccinocarboxamide synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in 'de novo' IMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
multifunctional protein ADE2
Names
Multifunctional protein ADE2
phosphoribosylaminoimidazole carboxylase; phosphoribosylaminoimidazolesuccinocarboxamide synthase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003615992.1 Reference CriGri_1.0 Primary Assembly

    Range
    47612..61610
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016963184.1 → XP_016818673.1  multifunctional protein ADE2 isoform X3

    UniProtKB/TrEMBL
    A0A8C2QN90
    Conserved Domains (2) summary
    cd01416
    Location:1 → 209
    SAICAR_synt_Ade5; Ade5_like 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase
    TIGR01162
    Location:219 → 372
    purE; phosphoribosylaminoimidazole carboxylase, PurE protein

  2. XM_007653814.4 → XP_007652004.1  multifunctional protein ADE2 isoform X3

    UniProtKB/TrEMBL
    A0A8C2QN90
    Conserved Domains (2) summary
    cd01416
    Location:1 → 209
    SAICAR_synt_Ade5; Ade5_like 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase
    TIGR01162
    Location:219 → 372
    purE; phosphoribosylaminoimidazole carboxylase, PurE protein

  3. XM_003513528.5 → XP_003513576.1  multifunctional protein ADE2 isoform X2

    UniProtKB/TrEMBL
    M1R995
    Conserved Domains (2) summary
    cd01416
    Location:7 → 258
    SAICAR_synt_Ade5; Ade5_like 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase
    TIGR01162
    Location:268 → 421
    purE; phosphoribosylaminoimidazole carboxylase, PurE protein

  4. XM_007653813.2 → XP_007652003.1  multifunctional protein ADE2 isoform X1

    UniProtKB/TrEMBL
    M1R995
    Conserved Domains (2) summary
    cd01416
    Location:50 → 301
    SAICAR_synt_Ade5; Ade5_like 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase
    TIGR01162
    Location:311 → 464
    purE; phosphoribosylaminoimidazole carboxylase, PurE protein

Alternate CriGri-PICRH-1.0

Genomic

  1. NW_023276807.1 Alternate CriGri-PICRH-1.0

    Range
    143371545..143385543
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027390947.1 → XP_027246748.1  multifunctional protein ADE2 isoform X6

    UniProtKB/TrEMBL
    A0A8C2QN90, A0A9J7J9S3
    Related
    ENSCGRP00015010511.1, ENSCGRT00015012909.2

  2. XM_027390948.2 → XP_027246749.1  multifunctional protein ADE2 isoform X6

    UniProtKB/TrEMBL
    A0A8C2QN90, A0A9J7J9S3

  3. XM_027390946.2 → XP_027246747.1  multifunctional protein ADE2 isoform X5

    UniProtKB/TrEMBL
    M1R995, M1RNR0
    Related
    ENSCGRP00015010490.1, ENSCGRT00015012889.2

  4. XM_027390945.1 → XP_027246746.1  multifunctional protein ADE2 isoform X4

    UniProtKB/TrEMBL
    A0A9J7F414, M1R995
Nucleotide Protein Strain
Heading Accession and Version

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