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Hmbs hydroxymethylbilane synthase [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100757819, updated on 8-Mar-2024

Summary

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Gene symbol
Hmbs
Gene description
hydroxymethylbilane synthase
Locus tag
I79_020104
See related
Ensembl:ENSCGRG00015014993
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
human mouse all
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Genomic context

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See Hmbs in Genome Data Viewer
Location:
chromosome: 4
Exon count:
14
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003615154.1 (195090..203691, complement)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 4 NC_048597.1 (156024558..156033145, complement)

NW_003615154.1Genomic Context describing neighboring genes Neighboring gene dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 Neighboring gene histone H2AX Neighboring gene VPS11 core subunit of CORVET and HOPS complexes Neighboring gene uncharacterized LOC107978609

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylbilane synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in heme biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-pyrromethane cofactor linkage IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
porphobilinogen deaminase
Names
Porphobilinogen deaminase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003615154.1 Reference CriGri_1.0 Primary Assembly

    Range
    195090..203691 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_003511560.5 → XP_003511608.1  porphobilinogen deaminase

    UniProtKB/TrEMBL
    A0A8C2MMV9, A0A8C2MQX7
    Conserved Domains (2) summary
    PRK00072
    Location:18 → 344
    hemC; porphobilinogen deaminase; Reviewed
    cd13645
    Location:20 → 299
    PBP2_HuPBGD_like; Human porphobilinogen deaminase possess type 2 periplasmic binding protein fold

Alternate CriGri-PICRH-1.0

Genomic

  1. NC_048597.1 Alternate CriGri-PICRH-1.0

    Range
    156024558..156033145 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027411931.2 → XP_027267732.1  porphobilinogen deaminase

    UniProtKB/TrEMBL
    A0A8C2MQX7, A0A9J7JKE1
    Related
    ENSCGRP00015057165.1, ENSCGRT00015067424.1
Nucleotide Protein Strain
Heading Accession and Version

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