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Pklr pyruvate kinase L/R [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100755461, updated on 8-Mar-2024

Summary

Gene symbol
Pklr
Gene description
pyruvate kinase L/R
Locus tag
I79_007991
See related
Ensembl:ENSCGRG00015001906
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
Orthologs
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Genomic context

See Pklr in Genome Data Viewer
Location:
chromosome: 1
Exon count:
12
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613854.1 (311294..319755)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276806.1 (65406963..65415424, complement)

NW_003613854.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene farnesyl diphosphate synthase Neighboring gene 40S ribosomal protein S9-like Neighboring gene hyperpolarization activated cyclic nucleotide gated potassium channel 3 Neighboring gene CDC like kinase 2 Neighboring gene secretory carrier membrane protein 3

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables potassium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables pyruvate kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
pyruvate kinase PKLR
Names
pyruvate kinase isozymes R/L
pyruvate kinase liver and red blood cell
pyruvate kinase, liver and RBC

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003613854.1 Reference CriGri_1.0 Primary Assembly

    Range
    311294..319755
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007642237.3XP_007640427.1  pyruvate kinase PKLR isoform X1

    See identical proteins and their annotated locations for XP_007640427.1

    UniProtKB/TrEMBL
    A0A9J7F773, G3HC41
    Conserved Domains (2) summary
    cd00288
    Location:109597
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...
    TIGR01064
    Location:110594
    pyruv_kin; pyruvate kinase
  2. XM_003501584.4XP_003501632.1  pyruvate kinase PKLR isoform X2

    See identical proteins and their annotated locations for XP_003501632.1

    UniProtKB/TrEMBL
    A0A3L7IG89, G3HC41
    Conserved Domains (1) summary
    cd00288
    Location:85573
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

Alternate CriGri-PICRH-1.0

Genomic

  1. NW_023276806.1 Alternate CriGri-PICRH-1.0

    Range
    65406963..65415424 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027393201.2XP_027249002.1  pyruvate kinase PKLR isoform X2

    UniProtKB/TrEMBL
    A0A3L7IG89, G3HC41
    Related
    ENSCGRP00015002383.1, ENSCGRT00015002961.2
  2. XM_027393204.2XP_027249005.1  pyruvate kinase PKLR isoform X1

    UniProtKB/TrEMBL
    A0A9J7F773, G3HC41
    Related
    ENSCGRP00015002392.2, ENSCGRT00015002974.2