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LOC100753528 RT1 class I histocompatibility antigen, AA alpha chain [ Cricetulus griseus (Chinese hamster) ]

Gene ID: 100753528, updated on 19-Dec-2023

Summary

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Gene symbol
LOC100753528
Gene description
RT1 class I histocompatibility antigen, AA alpha chain
Locus tag
I79_013138
Gene type
protein coding
RefSeq status
MODEL
Organism
Cricetulus griseus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
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Genomic context

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Location:
chromosome: 1
Exon count:
5
Annotation release Status Assembly Chr Location
104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003614196.1 (2296..5524)
104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276806.1 (229381084..229384325)

NW_003614196.1Genomic Context describing neighboring genes Neighboring gene H-2 class I histocompatibility antigen, Q10 alpha chain-like Neighboring gene ubiquitin-conjugating enzyme E2 L3-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables peptide antigen binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in antigen processing and presentation of endogenous peptide antigen via MHC class Ib IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of T cell mediated cytotoxicity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
H-2 class I histocompatibility antigen, Q9 alpha chain; RT1 class I histocompatibility antigen, AA alpha chain
Names
H-2 class I histocompatibility antigen, D-D alpha chain

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CriGri_1.0 Primary Assembly

Genomic

  1. NW_003614196.1 Reference CriGri_1.0 Primary Assembly

    Range
    2296..5524
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035458026.1 → XP_035313917.1  H-2 class I histocompatibility antigen, Q9 alpha chain isoform X1

    UniProtKB/TrEMBL
    G3HQN2
    Conserved Domains (2) summary
    pfam00129
    Location:24 → 202
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
    cl41775
    Location:206 → 247
    JMTM_Notch_APP; juxtamembrane and transmembrane (JMTM) domain found in Notch and APP family proteins

Alternate CriGri-PICRH-1.0

Genomic

  1. NW_023276806.1 Alternate CriGri-PICRH-1.0

    Range
    229381084..229384325
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_035450943.1 → XP_035306834.1  RT1 class I histocompatibility antigen, AA alpha chain isoform X2

    UniProtKB/TrEMBL
    A0A9J7KE36
    Conserved Domains (3) summary
    pfam00129
    Location:24 → 202
    MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2
    cd07698
    Location:206 → 297
    IgC1_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain, alpha3 immunoglobulin domain; member of the C1-set of Ig superfamily (IgSF) domains
    cl41775
    Location:298 → 339
    JMTM_Notch_APP; juxtamembrane and transmembrane (JMTM) domain found in Notch and APP family proteins
Nucleotide Protein Strain
Heading Accession and Version

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